About: dehydroepiandrosterone sulfate     Goto   Sponge   NotDistinct   Permalink

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  • DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia. (en)
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  • # Altman R, Motton DD, Kota RS, Rutledge JC: Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: Roles of PPARalpha and NF-kappaB. Vascul Pharmacol. 2007 Dec 15;. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/18255343 # Rabijewski M, Papierska L, Kozakowski J, Zgliczynski W: [The relationship between androgens concentrations (testosterone and dehydroepiandrosterone sulfate) and metabolic syndrome in non-obese elderly men.] Endokrynol Pol. 2007;58(6):496-504. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/18205106 # Geyer J, Doring B, Meerkamp K, Ugele B, Bakhiya N, Fernandes CF, Godoy JR, Glatt H, Petzinger E: Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6). J Biol Chem. 2007 Jul 6;282(27):19728-41. Epub 2007 May 9. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17491011 (en)
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  • investigational (en)
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  • Investigated for use/treatment in asthma and burns and burn infections. (en)
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Title
  • dehydroepiandrosterone sulfate (en)
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  • The low levels of dehydroepiandrosterone sulfate(DHEA-S)is associated with unfavorable levels of several strong cardiovascular disease risk factors, such as lipids and blood pleasure, which are components of the metabolic syndrome, and insulin levels. DHEA-S deficiency is risk factors of obesity and insulin resistance, but it is not clear, whether this possible influence is independent. (en)
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