About: Permethrin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid. (en)
http://linked.open...y/drugbank/dosage
http://linked.open...generalReferences
  • # Abedin S, Narang M, Gandhi V, Narang S: Efficacy of permethrin cream and oral ivermectin in treatment of scabies. Indian J Pediatr. 2007 Oct;74(10):915-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17978449 (en)
http://linked.open...gy/drugbank/group
  • approved (en)
  • investigational (en)
http://linked.open...ugbank/indication
  • For the treatment of infestation with <i>Sarcoptes scabiei</i> (scabies). (en)
sameAs
Title
  • Permethrin (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Permethrin acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization and paralysis of the pests are the consequences of this disturbance. (en)
http://linked.open...drugbank/packager
http://linked.open...outeOfElimination
  • Permethrin is rapidly metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in the urine. (en)
http://linked.open.../drugbank/synonym
  • Permethrin (en)
  • (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate (en)
  • 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester (en)
http://linked.open...drugbank/toxicity
  • Oral, rat LD<sub>50</sub>: 430 - 4000 mg/kg; skin, rabbit LD<sub>50</sub>: 2000 mg/kg. (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • Poorly absorbed through the skin. (en)
http://linked.open.../affectedOrganism
  • Scabies (Sarcoptes scabei) and other insects (en)
http://linked.open...casRegistryNumber
  • 52645-53-1 (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...ank/Boiling-Point
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...-strongest-basic-
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