| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - Ticrynafen, or tienilic acid, is a diuretic drug with uric acid-lowering (uricosuric) action, formerly marketed for the treatment of hypertension. It was withdrawn in 1982, shortly after its introduction to the market, after case reports in the United States indicated a link between the use of ticrynafen and hepatitis. (Manier et al., 1982) (en)
|
| http://linked.open...generalReferences
| - # Manier JW, Chang WW, Kirchner JP, Beltaos E: Hepatotoxicity associated with ticrynafen--a uricosuric diuretic. Am J Gastroenterol. 1982 Jun;77(6):401-4. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/7091125 (en)
|
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...ugbank/indication
| - For the treatment of hypertension. (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open.../drugbank/synonym
| - Tienilic acid (en)
- (2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy)acetic acid (en)
- (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid (en)
- 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid (en)
- (2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid (en)
- Thienylic acid (en)
- 4-(2-Theonyl)-2,3-dichlorphenoxyessigsaeure (en)
- Acide tienilique (en)
- Acido tienilico (en)
- Acidum tienilicum (en)
- Tienilico acido (en)
|
| http://linked.open...ynthesisReference
| - Harold Graboyes, "Method for preparing ticrynafen." U.S. Patent US4107179, issued April, 1977. (en)
|
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
| http://linked.open.../Molecular-Weight
| |
| http://linked.open...noisotopic-Weight
| |
| http://linked.open...y/drugbank/SMILES
| |
| http://linked.open.../Water-Solubility
| |
| http://linked.open...ogy/drugbank/logP
| |
| http://linked.open...ogy/drugbank/logS
| |
| http://linked.open...nd-Acceptor-Count
| |
| http://linked.open...-Bond-Donor-Count
| |
| http://linked.open...drugbank/InChIKey
| |
| http://linked.open...urface-Area--PSA-
| |
| http://linked.open...nk/Polarizability
| |
| http://linked.open...bank/Refractivity
| |
| http://linked.open...atable-Bond-Count
| |
| http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
|
| http://linked.open...casRegistryNumber
| |
| http://linked.open...drugbank/category
| |
| http://linked.open...k/Bioavailability
| |
| http://linked.open...bank/Ghose-Filter
| |
| http://linked.open...nk/MDDR-Like-Rule
| |
| http://linked.open...ank/Melting-Point
| |
| http://linked.open...k/Number-of-Rings
| |
| http://linked.open...siological-Charge
| |
| http://linked.open...bank/Rule-of-Five
| |
| http://linked.open...tional-IUPAC-Name
| |
| http://linked.open...strongest-acidic-
| |
| http://linked.open...-strongest-basic-
| |
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