About: Cycloleucine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Cycloleucine is an amino acid formed by cyclization of leucine. Cycloleucine is a non-metabolisable amino acid and is a specific and reversible inhibitor of nucleic acid methylation, and as such is widely used in biochemical experiments. [Wikipedia] (en)
http://linked.open...generalReferences
  • # Herberg LJ, Rose IC: Effects of D-cycloserine and cycloleucine, ligands for the NMDA-associated strychnine-insensitive glycine site, on brain-stimulation reward and spontaneous locomotion. Pharmacol Biochem Behav. 1990 Aug;36(4):735-8. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/2170997 (en)
http://linked.open...gy/drugbank/group
  • experimental (en)
sameAs
Title
  • Cycloleucine (en)
adms:identifier
http://linked.open.../drugbank/synonym
  • 1-Amino-1-cyclopentanecarboxylic acid (en)
  • 1-Amino-cyclopentanecarboxylic acid (en)
  • 1-Aminocyclopentane-1-carboxylic acid (en)
  • 1-Aminocyclopentanecarboxylate (en)
  • 1-Aminocyclopentanecarboxylic acid (en)
  • Amino-1-cyclopentanecarboxylic acid (en)
  • Cyclo-leucine (en)
  • Cycloleucin (en)
http://linked.open...drugbank/toxicity
  • Oral, mouse: LD<sub>50</sub> = 309 mg/kg; oral, rat: LD<sub>50</sub> = 290 mg/kg (en)
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...logy/drugbank/pKa
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 52-52-8 (en)
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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