About: Polystyrene sulfonate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV. [Wikipedia] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • none (en)
http://linked.open...ugbank/indication
  • Used to treat abnormally high potassium levels. (en)
sameAs
Title
  • Polystyrene sulfonate (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Polystyrene sulfonate, which is not absorbed, binds excess potassium, carrying it out of the body. The indigestible potassium polystryene sulfonate complex is excreted with the faeces, preventing the absorption of potassium into the blood stream. Hence, the serum potassium level decreases. (en)
http://linked.open...drugbank/packager
http://linked.open...outeOfElimination
  • Feces. (en)
http://linked.open...drugbank/toxicity
  • Overdose symptoms may include confusion, irritability, trouble thinking or concentrating, muscle weakness, or trouble breathing. (en)
http://linked.open...k/foodInteraction
  • Avoid calcium, magnesium and potassium. (en)
  • Take on an empty stomach. (en)
http://linked.open...ogy/drugbank/salt
  • (en)
http://linked.open...ynthesisReference
  • Chris Ho, Jugminder Chawla, Hitesh R. Bhagat, "Polystyrene sulfonate polymer tablets, their preparation and use." U.S. Patent US20080299198, issued December 04, 2008. (en)
http://linked.open...l/drug/hasATCCode
http://linked.open...ugbank/absorption
  • Not absorbed following oral administration. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 28210-41-5 (en)
http://linked.open...gbank/containedIn
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