About: Cefoxitin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by <i>Streptomyces lactamdurans</i>. (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • The half-life after an intravenous dose is 41 to 59 minutes. (en)
http://linked.open...ugbank/indication
  • For the treatment of serious infections caused by susceptible strains microorganisms. (en)
sameAs
Title
  • Cefoxitin (en)
adms:identifier
http://linked.open...mechanismOfAction
  • The bactericidal action of cefoxitin results from inhibition of cell wall synthesis. (en)
http://linked.open...drugbank/packager
http://linked.open...outeOfElimination
  • Approximately 85 percent of cefoxitin is excreted unchanged by the kidneys over a 6-hour period, resulting in high urinary concentrations. Cefoxitin passes into pleural and joint fluids and is detectable in antibacterial concentrations in bile. (en)
http://linked.open.../drugbank/synonym
  • Cefoxitin (en)
  • (6R,7S)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (en)
  • CFX (en)
  • Cefoxitina (en)
  • Cefoxitine (en)
  • Cefoxitinum (en)
  • Ceftoxitin (en)
  • Cephoxitin (en)
  • Rephoxitin (en)
http://linked.open...drugbank/toxicity
  • The acute intravenous LD50 in the adult female mouse and rabbit was about 8.0 g/kg and greater than 1.0 g/kg, respectively. The acute intraperitoneal LD50 in the adult rat was greater than 10.0 g/kg. (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...ynthesisReference
  • Pandurang Deshpande, Bhausaheb Khadangale, "Process for the preparation of cefoxitin." U.S. Patent US20060252928, issued November 09, 2006. (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open.../affectedOrganism
  • Enteric bacteria and other eubacteria (en)
http://linked.open...casRegistryNumber
  • 35607-66-0 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
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http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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