About: Bicalutamide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It binds to the androgen receptor. (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 5.9 days (en)
http://linked.open...ugbank/indication
  • For treatment (together with surgery or LHRH analogue) of advanced prostatic cancer. (en)
sameAs
Title
  • Bicalutamide (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue. (en)
http://linked.open...drugbank/packager
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  • Casodex (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...k/foodInteraction
  • Take without regard to meals, at the same time everyday. (en)
http://linked.open...nk/proteinBinding
  • 96% (en)
http://linked.open...ynthesisReference
  • Nnochiri Ekwuribe, "METHODS OF SYNTHESIZING ACYLANILIDES INCLUDING BICALUTAMIDE AND DERIVATIVES THEREOF." U.S. Patent US20020165406, issued November 07, 2002. (en)
foaf:page
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  • Bicalutamide is well-absorbed following oral administration, although the absolute bioavailability is unknown. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 90357-06-5 (en)
http://linked.open...rugbank/clearance
  • * Apparent oral cl=0.32 L/h [Normal Males] (en)
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http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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