About: Diphenhydramine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B611B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B611C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B611D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B611E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B611F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6120-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6121-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6122-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6123-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6124-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6125-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6126-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6127-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6128-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6129-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B612A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B612B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B612C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B612D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B612E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B612F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6130-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6131-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6132-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Raphael GD, Angello JT, Wu MM, Druce HM: Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2006 Apr;96(4):606-14. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/16680933 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	1-4 hours (en)
http://linked.open...ugbank/indication	For the treatment of symptoms associated with Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite. (en)
sameAs	Diphenhydramine
Title	Diphenhydramine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/chebi/4636 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/chemspider/2989 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/drugbank/DB01075 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/guide-to-pharmacology/1224 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/iuphar/1224 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/kegg-drug/D00300 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/national-drug-code-directory/0121-0489-05 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/pdb/2PM http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/pharmgkb/PA449349 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/pubchem-compound/3100 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/pubchem-substance/46505484 http://linked.opendata.cz/resource/drugbank/drug/DB01075/identifier/wikipedia/Diphenhydramine
http://linked.open...mechanismOfAction	Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. (en)
http://linked.open...drugbank/packager	Cardinal Health Carlisle Laboratories Inc. Chattem Chemicals Inc. Concord Labs Consolidated Midland Corp. Contract Pharm CVS Pharmacy Darby Dental Supply Co. Inc. Dept Health Central Pharmacy Actavis mid atlantic llc DispenseXpress Inc. Dispensing Solutions Diversified Healthcare Services Inc. Eon Labs Equaline Vitamins Eisai Inc. General Injectables and Vaccines Inc. GlaxoSmithKline Inc. Goldline Laboratories Inc. Heartland Repack Services LLC Hospira Inc. Innoviant Pharmacy Inc. Akorn Inc. Allergan Inc. Apotex Inc. Bausch & Lomb Inc. Major Pharmaceuticals Martin Surgical Supply McNeil Laboratories Medique Products Bausch and lomb inc Akorn inc Alcon inc Apotex inc etobicoke site Murfreesboro Pharmaceutical Nursing Supply Nexgen Pharma Inc. North Safety Products Nucare Pharmaceuticals Inc. Patient First Corp. PCA LLC PD-Rx Pharmaceuticals Inc. Perrigo Co. Pfizer Inc. Pharmaceutical Association Pharmedix Physicians Total Care Inc. Poly Pharmaceuticals Inc. Patheon Inc. Prepackage Specialists Prepak Systems Inc. Prescript Pharmaceuticals Procter & Gamble Provident Pharmaceuticals LLC Remedy Repack Heritage pharmaceuticals inc

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