About: Promethazine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B5F99-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5F9A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5F9B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5F9C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5F9D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5F9E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5F9F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA0-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA1-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA2-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA8-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5FA9-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Peters RJ Jr, Kelder SH, Markham CM, Yacoubian GS Jr, Peters LA, Ellis A: Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) onset and perceived addiction among urban Houstonian adolescents: an addiction trend in the city of lean. J Drug Educ. 2003;33(4):415-25. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15237866 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	16-19 hours (en)
http://linked.open...ugbank/indication	For the treatment of allergic disorders, and nausea/vomiting. (en)
sameAs	Promethazine
Title	Promethazine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/chebi/8461 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/chemspider/4758 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/drugbank/DB01069 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/kegg-compound/C07404 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/kegg-drug/D00494 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/national-drug-code-directory/0143-9869-22 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/pubchem-compound/4927 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/pubchem-substance/46507798 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/pharmgkb/PA451128 http://linked.opendata.cz/resource/drugbank/drug/DB01069/identifier/wikipedia/Promethazine
http://linked.open...mechanismOfAction	Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscle. The relief of nausea appears to be related to central anticholinergic actions and may implicate activity on the medullary chemoreceptor trigger zone. (en)
http://linked.open...drugbank/packager	Dispensing Solutions Diversified Healthcare Services Inc. Ebewe Pharma Alpharma us pharmaceuticals division Astrazeneca lp Baxter healthcare corp Dey lp H.J. Harkins Co. Inc. Heartland Repack Services LLC Hi Tech Pharmacal Co. Inc. Cardinal Health Carlisle Laboratories Inc. Century Pharmaceuticals Inc. Clint Pharmaceutical Inc. Comprehensive Consultant Services Inc. Consolidated Midland Corp. Corepharma LLC PD-Rx Pharmaceuticals Inc. DHHS Program Support Center Supply Service Center Direct Dispensing Inc. Hikma Pharmaceuticals Hospira Inc. Impax Laboratories Inc. Innoviant Pharmacy Inc. Ivax Pharmaceuticals Kaiser Foundation Hospital Keltman Pharmaceuticals Inc. KVK-Tech Inc. Lake Erie Medical and Surgical Supply Lark Pharmaceuticals Inc. Liberty Pharmaceuticals Major Pharmaceuticals Janssen-Ortho Inc. McNeil Laboratories Novopharm Ltd. Actavis Group Actavis Group Advanced Pharmaceutical Services Inc. Aidarex Pharmacuticals LLC Actavis totowa llc Apotheca Inc. A-S Medication Solutions LLC Sandoz Baxter International Inc. Bioniche Pharma Barr laboratories inc Actavis mid atlantic llc C.O. Truxton Inc. Cadila Healthcare Ltd. Pfizer Inc. Amend A-S Medication Solutions LLC Avanthi inc Corepharma llc Kaiser Foundation Hospital Murfreesboro Pharmaceutical Nursing Supply Advanced Pharmaceutical Services Inc. Abbott laboratories pharmaceutical products div AQ Pharmaceuticals Inc. A-S Medication Solutions LLC Dept Health Central Pharmacy Dispensing Solutions Diversified Healthcare Services Inc. H.J. Harkins Co. Inc.

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