| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - Isopropyl analog of epinephrine; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [PubChem] (en)
|
| http://linked.open...y/drugbank/dosage
| |
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...ugbank/indication
| - For the treatment of mild or transient episodes of heart block that do not require electric shock or pacemaker therapy also used in management of asthma and chronic bronchitis (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open...outeOfElimination
| - Excretion following inhalation administration is primarily renal and the major metabolite is the sulfate conjugate of isoproterenol. (en)
|
| http://linked.open.../drugbank/synonym
| - Isoprenaline (en)
- Isoproterenol (en)
- N-Isopropylnoradrenaline (en)
- N-Isopropylnorepinephrine (en)
- (+-)-Isoprenaline (en)
- (+-)-Isoproterenol (en)
- (±)-isoprenaline (en)
- (±)-isoproterenol (en)
- 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol (en)
- 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol (en)
- Isoprenalina (en)
- Isoprenalinum (en)
- Isopropyl noradrenaline (en)
- alpha-(Isopropylaminomethyl)protocatechuyl alcohol (en)
- 3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol (en)
- N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine (en)
- α-(isopropylaminomethyl)protocatechuyl alcohol (en)
- N-isopropyl-β-dihydroxyphenyl-β-hydroxyethylamine (en)
|
| http://linked.open.../drug/hasAHFSCode
| |
| http://linked.open...ogy/drugbank/salt
| |
| http://linked.open...ynthesisReference
| - U.S. Patent 2,308,232. U.S. Patent 2,715,141. (en)
|
| foaf:page
| |
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
| http://linked.open.../Molecular-Weight
| |
| http://linked.open...noisotopic-Weight
| |
| http://linked.open...y/drugbank/SMILES
| |
| http://linked.open.../Water-Solubility
| |
| http://linked.open...ogy/drugbank/logP
| |
| http://linked.open...ogy/drugbank/logS
| |
| http://linked.open...l/drug/hasATCCode
| |
| http://linked.open...nd-Acceptor-Count
| |
| http://linked.open...-Bond-Donor-Count
| |
| http://linked.open...drugbank/InChIKey
| |
| http://linked.open...urface-Area--PSA-
| |
| http://linked.open...nk/Polarizability
| |
| http://linked.open...bank/Refractivity
| |
| http://linked.open...atable-Bond-Count
| |
| http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
|
| http://linked.open...casRegistryNumber
| |
| http://linked.open...drugbank/category
| |
| http://linked.open...gbank/containedIn
| |
| http://linked.open...k/Bioavailability
| |
| http://linked.open...bank/Ghose-Filter
| |
| http://linked.open...nk/MDDR-Like-Rule
| |
| http://linked.open...ank/Melting-Point
| |
| http://linked.open...k/Number-of-Rings
| |
| http://linked.open...siological-Charge
| |
| http://linked.open...bank/Rule-of-Five
| |
| http://linked.open...tional-IUPAC-Name
| |
| http://linked.open...strongest-acidic-
| |
| http://linked.open...-strongest-basic-
| |
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