About: Ethiodized oil     Goto   Sponge   NotDistinct   Permalink

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  • Ethiodized oil is used by injection as a radio-opaque contrast agent. It is composed of iodine combined with ethyl esters of fatty acids of poppyseed oil, primarily as ethyl monoiodostearate and ethyl diiodostearate. The precise structure is not known. (en)
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http://linked.open...generalReferences
  • # "Link":http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=355795 # Nelson RC: Techniques for computed tomography of the liver. Radiol Clin North Am. 1991 Nov;29(6):1199-212. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1947041 # Hamm B, Wolf KJ: Contrast material for computed tomography and magnetic resonance imaging of the gastrointestinal tract. Curr Opin Radiol. 1991 Jun;3(3):474-82. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1859783 (en)
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  • approved (en)
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  • For use as a radio-opaque medium for hysterosalpingography and lymphography, and as an antineoplastic agent when part of the iodine is 131-I. It is also used in follow-up imaging for chemoembolization. (en)
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Title
  • Ethiodized oil (en)
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  • Ethiodized oil is selectively retained in tumor vessels for long periods, and is used for imaging organs such as liver, lung, stomach, and thyroid. Labeled with I-131 or other beta emitters (Y-90 or P-32), ethiodized oil can deliver a high internal radiation dose to certain tumors with minimal effect on healthy tissues. (en)
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  • Urinary excretion in the form of inorganic iodine was revealed as the chief mode of iodine loss from the system. (en)
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  • EOE 13 (en)
http://linked.open...drugbank/toxicity
  • Intravenous LD50 in dog is 1580mg/kg. Symptoms of overdose include dyspnea and change in clotting factors. (en)
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  • Humans and other mammals (en)
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  • 8008-53-5 (en)
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  • (en)
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