About: Famotidine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B62BE-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62BF-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C0-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C1-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C2-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62BA-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62BB-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62BC-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62BD-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B62C6-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2.5-3.5 hours (en)
http://linked.open...ugbank/indication	For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). (en)
http://linked.open...bank/manufacturer	Pharmedix Hospira Inc. Akorn Inc. Actavis elizabeth llc APP Pharmaceuticals Apotex inc Cardinal Health Baxter International Inc. Ivax pharmaceuticals inc sub teva pharmaceuticals usa Hollister-Stier Laboratories LLC Mylan pharmaceuticals inc Neuman Distributors Inc. Norwich Pharmaceuticals Inc. Pharmedium Sandoz Southwood Pharmaceuticals St Mary's Medical Park Pharmacy Stat Rx Usa Lupin ltd Medisca Inc. Baxter International Inc. Akorn strides llc Apotex inc richmond hill Apothecon inc div bristol myers squibb App pharmaceuticals llc Baxter healthcare corp anesthesia and critical care Baxter healthcare corp Halsey drug co inc Abbott laboratories pharmaceutical products div Ben Venue Laboratories Inc. Ben venue laboratories inc Claris lifesciences ltd Pharmaceutical Utilization Management Program VA Inc. Baxter International Inc.
sameAs	Famotidine
Title	Famotidine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/chebi/4975 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/chemspider/3208 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/drugbank/DB00927 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/kegg-drug/D00318 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/national-drug-code-directory/0006-3537-50 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/pharmgkb/PA449586 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/pubchem-compound/5702160 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/pubchem-substance/46507397 http://linked.opendata.cz/resource/drugbank/drug/DB00927/identifier/wikipedia/Famotidine
http://linked.open...mechanismOfAction	Famotidine binds competitively to H<sub>2</sub>-receptors located on the basolateral membrane of the parietal cell, blocking histamine affects. This competitive inhibition results in reduced basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. (en)
http://linked.open...drugbank/packager	Advanced Pharmaceutical Services Inc. Aidarex Pharmacuticals LLC Altura Pharmaceuticals Inc. Amerisource Health Services Corp. Abbott laboratories pharmaceutical products div APP Pharmaceuticals Apothecary Shop Wholesale A-S Medication Solutions LLC AstraZeneca Inc. Atlantic Biologicals Corporation Avkare Incorporated Bayer Healthcare Blenheim Pharmacal Bryant Ranch Prepack Cardinal Health App pharmaceuticals llc Baxter healthcare corp anesthesia and critical care Baxter healthcare corp anesthesia critical care Coupler Enterprises Inc. Bioniche pharma usa llc Sandoz Dept Health Central Pharmacy Alembic ltd Barr laboratories inc B braun medical inc Pharmaceutical Utilization Management Program VA Inc. Bedford laboratories Elan Pharmaceuticals Inc. Ivax pharmaceuticals inc sub teva pharmaceuticals usa F Hoffmann-La Roche Ltd. Glenmark Generics Ltd. Golden State Medical Supply Inc. Group Health Cooperative H.J. Harkins Co. Inc. Heartland Repack Services LLC

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