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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed. (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 6-14 hours. (en)
http://linked.open...ugbank/indication
  • For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Sulfapyridine (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Sulfapyridine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid by means of processing the substrate para-aminobenzoic acid (PABA). Dihydropteroate synthetase activity is vital in the synthesis of folate, and folate is required for cells to make nucleic acids, such as DNA or RNA. So if DNA molecules cannot be built, the cell cannot divide. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Sulfapyridine (en)
  • Streptosilpyridine (en)
  • 2-Sulfanilamidopyridin (en)
  • 2-Sulfanilamidopyridine (en)
  • 2-Sulfanilylaminopyridine (en)
  • 2-Sulfapyridine (en)
  • 4-(2-Pyridinylsulfonyl)aniline (en)
  • 4-[(2-Pyridylamino)sulfonyl]aniline (en)
  • N-2-Pyridylsulfanilamide (en)
  • Sulphapyridine (en)
  • 2-(P-Aminobenzenesulphonamido)pyridine (en)
  • 4-Amino-N,2-pyridinylbenzenesulfonamide (en)
  • 4-Amino-N-pyridin-2-yl-benzenesulfonamide (en)
  • N(1)-2-Pyridylsulfanilamide (en)
  • N(1)-Pyridylsulfanilamide (en)
  • Solfapiridina (en)
  • Sulfapiridina (en)
  • Sulfapyridin (en)
  • Sulfapyridinum (en)
http://linked.open...drugbank/toxicity
  • LD<sub>50</sub> is 15800 mg/kg (orally in rats). (en)
http://linked.open.../drugbank/mixture
http://linked.open...nk/proteinBinding
  • Approximately 50% bound to plasma proteins. (en)
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...logy/drugbank/pKa
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • Approximately 60-80% (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 144-83-2 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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