About: Ranitidine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B51A9-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5196-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5197-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5198-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5199-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B519A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B519B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B519C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B519D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B519E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B519F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A0-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A1-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A2-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B51A8-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2.8-3.1 hours (en)
http://linked.open...ugbank/indication	Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD). (en)
http://linked.open...bank/manufacturer	Dr reddys laboratories ltd Genpharm inc Sandoz inc Teva pharmaceuticals usa inc Glaxosmithkline Bedford laboratories div ben venue laboratories inc Ben venue laboratories inc Actavis mid atlantic llc Amneal pharmaceuticals Apotex inc Altana inc Pharmaceutical assoc inc div beach products Ranbaxy laboratories ltd Hi tech pharmacal co inc Perrigo co Boehringer ingelheim pharmaceuticals inc Amneal pharmaceuticals ny llc Boehringer ingelheim corp Contract pharmacal corp Dr reddys laboratories inc Actavis Group Ivax pharmaceuticals inc sub teva pharmaceuticals usa Amneal Pharmaceuticals Aristos Pharmaceuticals A-S Medication Solutions LLC Advanced Pharmaceutical Services Inc. Amerisource Health Services Corp. Apotex Inc. Apotheca Inc. Atlantic Biologicals Corporation Aurobindo pharma usa inc
sameAs	Ranitidine
Title	Ranitidine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/bindingdb/22893 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/chebi/8776 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/chemspider/2272523 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/drugbank/DB00863 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/guide-to-pharmacology/1234 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/iuphar/1234 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/kegg-drug/D00422 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/national-drug-code-directory/0172-4357-49 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/pharmgkb/PA451224 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/pubchem-compound/3001055 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/pubchem-substance/46505543 http://linked.opendata.cz/resource/drugbank/drug/DB00863/identifier/wikipedia/Ranitidine
http://linked.open...mechanismOfAction	The H2 antagonists are competitive inhibitors of histamine at the parietal cell H2 receptor. They suppress the normal secretion of acid by parietal cells and the meal-stimulated secretion of acid. They accomplish this by two mechanisms: histamine released by ECL cells in the stomach is blocked from binding on parietal cell H2 receptors which stimulate acid secretion, and other substances that promote acid secretion (such as gastrin and acetylcholine) have a reduced effect on parietal cells when the H2 receptors are blocked. (en)
http://linked.open...drugbank/packager	Advanced Pharmaceutical Services Inc. Amerisource Health Services Corp. Apotex Inc. A-S Medication Solutions LLC AQ Pharmaceuticals Inc. A-S Medication Solutions LLC Banner Pharmacaps Inc. Pfizer Inc. Ben Venue Laboratories Inc. Blenheim Pharmacal Boehringer Ingelheim Ltd. Bryant Ranch Prepack Actavis totowa llc Cardinal Health Dept Health Central Pharmacy Dispensing Solutions Diversified Healthcare Services Inc. Doctor Reddys Laboratories Ltd. Amgen inc Fusion Pharmaceuticals LLC Genpharm LP Pharmaceutical Utilization Management Program VA Inc. Glenmark Generics Ltd. Golden State Medical Supply Inc. H.J. Harkins Co. Inc. Heartland Repack Services LLC Actavis Group Innovative Manufacturing and Distribution Services Inc. Amerisource Health Services Corp.

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