About: Dicyclomine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B3F82-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F83-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F84-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F85-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F86-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3F87-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For the treatment of functional bowel/irritable bowel syndrome including Colicky abdominal pain; diverticulitis (en)
http://linked.open...bank/manufacturer	AstraZeneca Inc. Amend American Regent Alpharma us pharmaceuticals division APP Pharmaceuticals Hospira Inc. Mutual pharmaceutical co inc Hospira inc Pioneer pharmaceuticals inc Adamis Laboratories
sameAs	Dicyclomine
Title	Dicyclomine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/bindingdb/50010101 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/chebi/4514 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/chemspider/2934 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/drugbank/DB00804 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/guide-to-pharmacology/355 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/iuphar/355 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/kegg-compound/C06951 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/national-drug-code-directory/0378-1610-01 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/pubchem-compound/3042 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/pubchem-substance/46505371 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/pharmgkb/PA164744928 http://linked.opendata.cz/resource/drugbank/drug/DB00804/identifier/wikipedia/Dicyclomine
http://linked.open...mechanismOfAction	Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic). (en)
http://linked.open...drugbank/packager	Advanced Pharmaceutical Services Inc. AstraZeneca Inc. Astrazeneca uk ltd EKR Therapeutics Inc. Hospira Inc. PDL BioPharma Inc. Amgen Inc. Centocor Ortho Biotech Inc. DSM Corp. Janssen-Ortho Inc. JHP Pharmaceuticals LLC Ortho-McNeil-Janssen Pharmaceuticals Inc. Amerisource Health Services Corp. Apotheca Inc. A-S Medication Solutions LLC Atlantic Biologicals Corporation Axcan Pharma Inc. Bryant Ranch Prepack Lannett Co. Inc. Liberty Pharmaceuticals Major Pharmaceuticals Merrell Pharmaceuticals Inc. Mikart Inc. Murfreesboro Pharmaceutical Nursing Supply Mylan Nucare Pharmaceuticals Inc. Palmetto Pharmaceuticals Inc. Patheon Inc. Patient First Corp. PCA LLC PD-Rx Pharmaceuticals Inc. Pharma Pac LLC Pharmedix Physicians Total Care Inc. Preferred Pharmaceuticals Inc. Prepackage Specialists Prepak Systems Inc. Remedy Repack Resource Optimization and Innovation LLC Santec Chemicals Corp. Southwood Pharmaceuticals Stat Rx Usa Taylor Pharmaceuticals Tya Pharmaceuticals Apotex Inc. 3m pharmaceuticals inc B. Braun Melsungen AG Baxter International Inc. Bioniche Pharma Diversified Healthcare Services Inc. Endo Pharmaceuticals Inc. Gallipot H.J. Harkins Co. Inc. Heartland Repack Services LLC Sagent Pharmaceuticals International Ethical Labs Inc.
http://linked.open...outeOfElimination	The principal route of elimination is via the urine (79.5% of the dose). Excretion also occurs in the feces, but to a lesser extent (8.4%). (en)
http://linked.open.../drugbank/synonym	Dicycloverine (en) Dicycloverin (en) DICYCLOMINE (en) Dicicloverina (en) Dicycloverinum (en) 2-(Diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate (en) Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester (en)
http://linked.open...umeOfDistribution	* 3.65 L/kg [20 mg oral dose] (en)

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