About: Meclizine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B5308-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5309-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B530A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B530B-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	6 hours (en)
http://linked.open...ugbank/indication	For the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness. (en)
http://linked.open...bank/manufacturer	Pfizer inc
sameAs	Meclizine
Title	Meclizine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/chemspider/3894 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/drugbank/DB00737 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/guide-to-pharmacology/2757 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/iuphar/2757 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/kegg-compound/C07116 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/national-drug-code-directory/0662-2100-66 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/pharmgkb/PA450338 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/pubchem-compound/4034 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/pubchem-substance/46507782 http://linked.opendata.cz/resource/drugbank/drug/DB00737/identifier/wikipedia/Meclizine
http://linked.open...mechanismOfAction	Along with its actions as an antagonist at H<sub>1</sub>-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Meclizine depresses labyrinth excitability and vestibular stimulation and may affect the medullary chemoreceptor trigger zone. (en)
http://linked.open...drugbank/packager	Pharmaceutical Utilization Management Program VA Inc. Aidarex Pharmacuticals LLC A-S Medication Solutions LLC Apotheca Inc. 3M Health Care Apotex Inc. Altana inc Blenheim Pharmacal Breckenridge Pharmaceuticals Bryant Ranch Prepack C.O. Truxton Inc. Actavis mid atlantic llc Carlisle Laboratories Inc. Banner pharmacaps inc Century Pharmaceuticals Inc. Cerovene Inc. Comprehensive Consultant Services Inc. Pharmaceutical Utilization Management Program VA Inc. Acton pharmaceuticals inc Apotex inc richmond hill Bausch and lomb pharmaceuticals inc Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Duramed Eon Labs Glenmark Generics Ltd. Sandoz Great Southern Laboratories H and H Laboratories H.J. Harkins Co. Inc. Heartland Repack Services LLC Hi Tech Pharmacal Co. Inc. Hospira Inc. Innoviant Pharmacy Inc. Ivax Pharmaceuticals Pfizer Inc. Pharmaceutical Utilization Management Program VA Inc. Impax laboratories inc Keltman Pharmaceuticals Inc. Lake Erie Medical and Surgical Supply Lannett Co. Inc. Lederle laboratories div american cyanamid co Liberty Pharmaceuticals Barr laboratories inc Mallinckrodt Inc. Mckesson Corp. Dr reddys laboratories ltd Medvantx Inc. Mikart Inc. Sandoz Mutual Pharmaceutical Co. Nexgen Pharma Inc. Novartis AG Nucare Pharmaceuticals Inc. Ortho-McNeil-Janssen Pharmaceuticals Inc. Bracco Diagnostics Inc. Nycomed Inc. Bracco diagnostics inc PD-Rx Pharmaceuticals Inc.
http://linked.open.../drugbank/synonym	Meclozine (en) Meclizine (en) Nevidoxine (en)
http://linked.open...drugbank/toxicity	Symptoms of overdose include drowsiness and anticholinergic effects. LD<sub>50</sub>=mg/kg (orally in rat). (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/56-22-08
http://linked.open...k/foodInteraction	Take with food to reduce irritation. Avoid alcohol. (en)
http://linked.open.../drugbank/mixture	Antivert Tab Emesafene
http://linked.open...ogy/drugbank/salt	(en)
http://linked.open...ynthesisReference	U.S. Patent 2,709,169. (en)
foaf:page	http://www.drugs.com/meclizine.html http://www.rxlist.com/cgi/generic/mecliz.htm
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B5310-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B5316-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B5315-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B5312-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B5313-363D-11E5-9242-09173F13E4C5

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