About: Moricizine

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About: Moricizine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	An antiarrhythmia agent used primarily for ventricular rhythm disturbances. [PubChem] (en)
http://linked.open...gy/drugbank/group	approved (en) withdrawn (en)
http://linked.open...drugbank/halfLife	2 hours (range 1.5-3.5 hours). (en)
http://linked.open...ugbank/indication	Used to treat irregular heartbeats (arrhythmias) and maintain a normal heart rate. (en)
http://linked.open...bank/manufacturer	Golden State Medical Supply Inc.
sameAs	Moricizine
Title	Moricizine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/chebi/6997 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/chemspider/31872 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/drugbank/DB00680 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/kegg-compound/C07743 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/kegg-drug/D05077 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/national-drug-code-directory/54092-046-01 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/pubchem-compound/34633 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/pubchem-substance/46509072 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/pharmgkb/PA164747738 http://linked.opendata.cz/resource/drugbank/drug/DB00680/identifier/wikipedia/Moricizine
http://linked.open...mechanismOfAction	Moricizine works by inhibiting the rapid inward sodium current across myocardial cell membranes. (en)
http://linked.open...drugbank/packager	Bristol-Myers Squibb Co.
http://linked.open...outeOfElimination	Less than 1% of orally administered Ethmozine® is excreted unchanged in the urine. Approximately 56% of the administered dose is excreted in the feces and 39% is excreted in the urine. (en)
http://linked.open.../drugbank/synonym	Moracizine (en) Moricizine (en) Moracizin (en) Ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate (en) EN-313 (en) Ethmozin (en) Etmozin (en) Moracizina (en) Moracizinum (en) Ethyl 10-(beta-N-morpholinylpropionyl)phenothiazine-2-carbamate (en) [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester (en)
http://linked.open...drugbank/toxicity	Symptoms of overdose include vomiting, unconsciousness, and severe low blood pressure. (en)
http://linked.open...umeOfDistribution	* 300 L (en)
http://linked.open...nk/proteinBinding	Approximately 95%. (en)
http://linked.open...ogy/drugbank/salt	(en)
http://linked.open...ynthesisReference	"DrugSyn.org":http://www.drugsyn.org/Moricizine.htm (en)
foaf:page	http://www.drugs.com/cdi/moricizine.html
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B4309-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B430F-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B430E-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B430B-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B430C-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B430D-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B4307-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B431F-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B4321-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B4305-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B4308-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B4306-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Moracizine
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B4315-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B4316-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B4310-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B4311-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B4313-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B4312-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B4314-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Well absorbed, absorption is complete within 2 to 3 hours. Significant first-pass metabolism results in an absolute bioavailability of approximately 38%. Administration within 30 minutes after a meal slows the rate, but does not affect the extent of absorption, although peak plasma concentrations are reduced. (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	31883-05-3 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B431B-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B431D-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B431E-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B4320-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B431A-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B4319-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B431C-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B430A-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B4317-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B4318-363D-11E5-9242-09173F13E4C5

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