About: Epinephrine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B3FDD-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FDE-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FDF-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FDA-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FDB-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FDC-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FCF-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD0-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD1-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD2-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD8-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B3FD9-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Yamashima T: Jokichi Takamine (1854-1922), the samurai chemist, and his work on adrenalin. J Med Biogr. 2003 May;11(2):95-102. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12717538 # Bennett MR: One hundred years of adrenaline: the discovery of autoreceptors. Clin Auton Res. 1999 Jun;9(3):145-59. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10454061 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2 minutes (en)
http://linked.open...ugbank/indication	Used to treat anaphylaxis and sepsis. Also one of the body's main adrenergic neurotransmitters. (en)
http://linked.open...bank/manufacturer	Auriga Pharmaceuticals LLC Baroli Bausch & Lomb Inc. Baxter International Inc. Bayer Healthcare Bio Pharm Inc. 3m pharmaceuticals inc Astrazeneca lp Breckenridge Pharmaceuticals Brookstone Pharmaceuticals
sameAs	Epinephrine
Title	Epinephrine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/chebi/28918 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/chemspider/5611 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/drugbank/DB00668 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/guide-to-pharmacology/479 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/iuphar/479 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/kegg-compound/C00788 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/kegg-drug/D00095 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/national-drug-code-directory/59630-803-01 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/pdb/ALE http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/pharmgkb/PA449470 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/pubchem-compound/5816 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/pubchem-substance/46509097 http://linked.opendata.cz/resource/drugbank/drug/DB00668/identifier/wikipedia/Epinephrine
http://linked.open...mechanismOfAction	Epinephrine works via the stimulation of alpha and beta-1 adrenergic receptors, and a moderate activity at beta-2 adrenergic receptors. (en)
http://linked.open...drugbank/packager	Apotex Inc. Mckesson Corp. Actavis Group Sandoz Aidarex Pharmacuticals LLC Amerisource Health Services Corp. Apotex Inc. Amend American Regent Alpharma us pharmaceuticals division APP Pharmaceuticals Armstrong Pharmaceuticals Inc. A-S Medication Solutions LLC Belport Co. Inc. Bioniche Pharma Cardinal Health Carestream Health Inc. APP Pharmaceuticals Bedford Labs Ben Venue Laboratories Inc. DENTSPLY International Deproco Inc. Dey Pharma LP Eastman Kodak Co. Dental Products General Injectables and Vaccines Inc. Greenstone LLC Henry Schein Inc. Hikma Pharmaceuticals Hollister-Stier Laboratories LLC Hospira Inc. JHP Pharmaceuticals LLC Jordan Pharmaceuticals Inc. Allergan pharmaceutical Accutome Inc. A-S Medication Solutions LLC Advanced Pharmaceutical Services Inc. Advanced Vision Research AG Marin Pharmaceuticals Akorn Inc. Alba Pharmacal Alcon Laboratories Apical Pharmaceutical Corporation Allergy Laboratories Inc. Altaire Pharmaceuticals APP Pharmaceuticals Amend A-S Medication Solutions LLC Pharmaceutical Utilization Management Program VA Inc. Anip Acquisition Co. A-S Medication Solutions LLC Athlon Pharmaceuticals Inc.

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