About: Verapamil

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A calcium channel blocker that is a class IV anti-arrhythmia agent. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B64CE-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64CF-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D0-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D1-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D2-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D8-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64D9-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64DA-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E1-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E8-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E9-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64EA-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64EB-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64EC-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64DB-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64DC-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64DD-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64DE-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64DF-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E0-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E2-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E4-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B64E5-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Bellamy WT: P-glycoproteins and multidrug resistance. Annu Rev Pharmacol Toxicol. 1996;36:161-83. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8725386 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2.8-7.4 hours (en)
http://linked.open...ugbank/indication	For the treatment of hypertension, angina, and cluster headache prophylaxis. (en)
http://linked.open...bank/manufacturer	Corepharma llc Dr reddys laboratories ltd Epic pharma llc Invagen pharmaceuticals inc Abraxis pharmaceutical products Mylan pharmaceuticals inc Hospira inc International medication system Luitpold pharmaceuticals inc Marsam pharmaceuticals llc Sandhills Packaging Inc. Solopak medical products inc Ranbaxy laboratories inc Glenmark generics ltd Ivax pharmaceuticals inc sub teva pharmaceuticals usa Par pharmaceutical inc Pliva inc Actavis elizabeth llc Heritage pharmaceuticals inc Mutual pharmaceutical co inc Hikma farmaceutica (portugal) sa Warner chilcott div warner lambert co Pharmaforce inc
sameAs	Verapamil
Title	Verapamil (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/bindingdb/50005628 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/chebi/9948 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/chemspider/2425 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/drugbank/DB00661 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/guide-to-pharmacology/2406 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/iuphar/2406 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/kegg-compound/C07188 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/kegg-drug/D02356 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/national-drug-code-directory/0091-4085-01 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/pharmgkb/PA451868 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/pubchem-compound/2520 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/pubchem-substance/46508158 http://linked.opendata.cz/resource/drugbank/drug/DB00661/identifier/wikipedia/Verapamil
http://linked.open...mechanismOfAction	Verapamil inhibits voltage-dependent calcium channels. Specifically, its effect on L-type calcium channels in the heart causes a reduction in ionotropy and chronotropy, thuis reducing heart rate and blood pressure. Verapamil's mechanism of effect in cluster headache is thought to be linked to its calcium-channel blocker effect, but which channel subtypes are involved is presently not known. (en)
http://linked.open...drugbank/packager	Apotheca Inc. Amerisource Health Services Corp. A-S Medication Solutions LLC Cardinal Health Caremark LLC Comprehensive Consultant Services Inc. Dispensing Solutions Greenstone LLC Dept Health Central Pharmacy Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Duramed Elan Pharmaceuticals Inc. Nucare Pharmaceuticals Inc. GD Searle LLC General Injectables and Vaccines Inc. Pfizer Inc. Golden State Medical Supply Inc. Group Health Cooperative H.J. Harkins Co. Inc. Kaiser Foundation Hospital Lake Erie Medical and Surgical Supply Liberty Pharmaceuticals

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