About: Nystatin

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Nystatin is a polyene antifungal drug to which many molds and yeasts are sensitive, including Candida spp. Nystatin has some toxicity associated with it when given intravenously, but it is not absorbed across intact skin or mucous membranes. It is considered a relatively safe drug for treating oral or gastrointestinal fungal infections. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B6050-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6051-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6052-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6053-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6054-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6055-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6056-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6057-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6058-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6059-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B605A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B605B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B605C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B605D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B605E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B605F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B6060-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Akaike N, Harata N: Nystatin perforated patch recording and its applications to analyses of intracellular mechanisms. Jpn J Physiol. 1994;44(5):433-73. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/7534361 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species (en)
http://linked.open...bank/manufacturer	Mutual Pharmaceutical Co. Mylan Novopharm Ltd. Bristol myers squibb Pharmaceutical Utilization Management Program VA Inc. Dava pharmaceuticals inc Par pharmaceutical inc United Research Laboratories Inc. Ortho mcneil janssen pharmaceuticals inc Actavis elizabeth llc Ivax pharmaceuticals inc sub teva pharmaceuticals usa Glenmark generics inc usa Bausch and lomb pharmaceuticals inc E fougera div altana inc Morton grove pharmaceuticals inc Pharmaderm div altana inc Pharmafair inc Roxane laboratories inc Apotheca Inc. Vistapharm inc Actavis Group Ameri-Pac Inc. Carlisle Laboratories Inc. Clint Pharmaceutical Inc. Consolidated Midland Corp. DPT Laboratories Ltd. Direct Dispensing Inc. Dispensing Solutions APP Pharmaceuticals Bayer pharmaceuticals corp Bristol myers squibb co Alpharma us pharmaceuticals division Ivax pharmaceuticals inc sub teva pharmaceuticals usa Actavis mid atlantic llc Altana inc Major Pharmaceuticals Murfreesboro Pharmaceutical Nursing Supply Paddock laboratories inc GE Healthcare Inc. Ge healthcare
sameAs	Nystatin
Title	Nystatin (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/chemspider/10128183 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/drugbank/DB00646 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/kegg-compound/C06572 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/kegg-drug/D00202 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/national-drug-code-directory/0574-2008-15 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/pharmgkb/PA450666 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/pubchem-compound/11953884 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/pubchem-substance/46504780 http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/wikipedia/Nystatin
http://linked.open...mechanismOfAction	Nystatin exerts its antifungal activity by binding to ergosterol found in fungal cell membranes. Binding to ergosterol causes the formation of pores in the membrane. Potassium and other cellular constituents leak from the pores causing cell death. (en)
http://linked.open...drugbank/packager	Apothecon A-S Medication Solutions LLC Atlantic Biologicals Corporation Bausch & Lomb Inc. Barr Pharmaceuticals Cardinal Health Contract Pharm Ivax Pharmaceuticals Dept Health Central Pharmacy Dispensing Solutions Pharmaceutical Utilization Management Program VA Inc. Duramed E. Fougera and Co. E.R. Squibb and Sons LLC Gallipot Glenmark Generics Ltd. Major Pharmaceuticals Genpharm inc Ivax pharmaceuticals inc sub teva pharmaceuticals usa Heather drug co inc Impax laboratories inc Mylan pharmaceuticals inc Par pharmaceutical inc Pfizer Inc. Advanced Pharmaceutical Services Inc. Aidarex Pharmacuticals LLC

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