About: Monobenzone

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About: Monobenzone Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. The topical application of monobenzone in animals increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation. (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	Used topically to treat the loss of skin color (vitiligo). (en)
http://linked.open...bank/manufacturer	Innovative Manufacturing and Distribution Services Inc.
sameAs	Monobenzone
Title	Monobenzone (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/chebi/34380 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/chemspider/7356 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/drugbank/DB00600 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/kegg-compound/C14244 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/kegg-drug/D05072 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/national-drug-code-directory/0187-0380-34 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/pubchem-compound/7638 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/pubchem-substance/46507466 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/pharmgkb/PA164764582 http://linked.opendata.cz/resource/drugbank/drug/DB00600/identifier/wikipedia/Monobenzone
http://linked.open...mechanismOfAction	Monobenzone is a depigmenting agent whose mechanism of action is not fully understood. The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation. This effect is erratic and may take one to four months to occur while existing melanin is lost with normal sloughing of the stratum corneum. Hyperpigmented skin appears to fade more rapidly than does normal skin, and exposure to sunlight reduces the depigmenting effect of the drug. The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes. (en)
http://linked.open...drugbank/packager	Baxter healthcare corp anesthesia critical care Elkins sinn div ah robins co inc Heartland Repack Services LLC
http://linked.open.../drugbank/synonym	Monobenzone (en) Benzyl p-hydroxyphenyl ether (en) Hydroquinone benzyl ether (en) Hydroquinone monobenzyl ether (en) Monobenzyl hydroquinone (en) p-Hydroxyphenyl benzyl ether (en) 4-(Benzyloxy)phenol (en) 4-(Benzyloxyl)phenol (en) 4-(Phenylmethoxy)phenol (en) 4-Benzyloxy-phenol (en) 4-Benzyloxyphenol (en) Hydrochinon monobenzylether (en) MONOBENZYL ether OF hydroquinone (en) Monobenzona (en) Monobenzonum (en) p-(Benzyloxy)phenol (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/84-50-04
foaf:page	http://www.drugs.com/mtm/monobenzone-topical.html
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B539F-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B53A5-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B53A4-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B53A1-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B53A2-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B53A3-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B53B5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B539D-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B53B7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B539B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B539E-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B539C-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Monobenzone
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B53AB-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B53AC-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B53A6-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B53A7-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B53A9-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B53A8-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B53AA-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	103-16-2 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Hydroquinone mono benzyl ether
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B53B1-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B53B3-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B53B4-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B53B6-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B53B0-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B53AF-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B53B2-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B53A0-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B53AD-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B53AE-363D-11E5-9242-09173F13E4C5

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