About: Methoxsalen     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. [PubChem] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • Approximately 2 hours (en)
http://linked.open...ugbank/indication
  • For the treatment of psoriasis and vitiligo (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Methoxsalen (en)
adms:identifier
http://linked.open...mechanismOfAction
  • After activation it binds preferentially to the guanine and cytosine moieties of DNA, leading to cross-linking of DNA, thus inhibiting DNA synthesis and function. (en)
http://linked.open...drugbank/packager
http://linked.open...outeOfElimination
  • In both mice and man, methoxsalen is rapidly metabolized. Approximately 95% of the drug is excreted as a series of metabolites in the urine within 24 hours (Pathak et al. 1977). (en)
http://linked.open.../drugbank/synonym
  • Methoxsalen (en)
  • Meladinine (en)
  • Meloxine (en)
  • Oxsoralen (en)
  • Uvadex (en)
  • Methoxalen (en)
  • Xanthotoxin (en)
  • Xanthotoxine (en)
  • Xanthoxin (en)
  • Zanthotoxin (en)
  • 8-Methoxypsoralen (en)
  • Ammoidin (en)
  • 8-MOP (en)
  • 8-MP (en)
  • 8-Methoxy-2',3',6,7-furocoumarin (en)
  • 8-Methoxy-4',5':6,7-furocoumarin (en)
  • 8-Methoxy-[furano-3'.2':6.7-coumarin] (en)
  • 8-Methoxyfuranocoumarin (en)
  • 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one (en)
  • Méthoxsalène (en)
  • O-Methylxanthotoxol (en)
  • Ultra mop (en)
  • 6-Hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...k/foodInteraction
  • Take with food or milk, or in two divided doses 30 minutes apart to decrease nausea. (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 298-81-7 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
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