About: Sodium Tetradecyl Sulfate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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http://linked.open...gbank/description
  • An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins. (en)
http://linked.open...y/drugbank/dosage
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  • approved (en)
http://linked.open...ugbank/indication
  • For the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Sodium Tetradecyl Sulfate (en)
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http://linked.open...mechanismOfAction
  • Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a considerable distance and exposing highly thrombogenic endothelium in the process. Diluted sodium tetradecyl sulfate is also able to induce a hypercoagulable state, possibly by selective inhibition of protein C, and can also promote platelet aggregation. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Tetradecyl sodium sulfate (en)
  • STS (en)
http://linked.open...drugbank/toxicity
  • LD<sub>50</sub>=1250 mg/kg (Orally in rat); LD<sub>50</sub>=3 ml/kg (Skin in rat) (en)
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  • Humans and other mammals (en)
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  • 1191-50-0 (en)
http://linked.open...drugbank/category
  • (en)
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