About: Dexbrompheniramine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Dexbrompheniramine maleate is an antihistamine used to treat allergic conditions such as hay fever or urticaria. (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 25 hours (en)
http://linked.open...ugbank/indication
  • For treatment and relief of symptoms of allergies, hay fever, and colds (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Dexbrompheniramine (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Dexbrompheniramine competitively binds to the histamine H<sub>1</sub>-receptor. It competes with histamine for the normal H<sub>1</sub>-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • D-Brompheniramine (en)
  • Parabromodylamine (en)
  • (+)-Brompheniraminum (en)
  • (+)-parabromdylamine (en)
  • (S)-(+)-Brompheniramine (en)
  • (S)-Brompheniramine (en)
  • Desbrofeniramina (en)
  • Dexbromfeniramina (en)
  • Dexbrompheniramin (en)
  • Dexbrompheniraminum (en)
  • Dexbromphéniramine (en)
  • 3-(4-bromophenyl)- N,N-dimethyl- 3-pyridin-2-yl-propan-1-amine (en)
  • (R)-3-(4-Bromophenyl)-3-(2-pyridyl)propyldimethylamine (en)
http://linked.open...drugbank/toxicity
  • Signs of an overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness. (en)
http://linked.open.../drugbank/mixture
http://linked.open...ynthesisReference
  • Walter, L.A.; U.S. Patents 3,061,517; October 30, 1962; and 3,030,371; April 17, 1962; both assigned to Schering Corporation. (en)
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • Antihistamines are well absorbed from the gastrointestinal tract after oral administration. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 132-21-8 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...-strongest-basic-
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