About: Phenylpropanolamine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Phenylpropanolamine has been withdrawn in Canada and the United States. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug. (en)
http://linked.open...gy/drugbank/group	approved (en) withdrawn (en)
http://linked.open...drugbank/halfLife	2.1 to 3.4 hours. (en)
http://linked.open...ugbank/indication	For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity. (en)
sameAs	Phenylpropanolamine
Title	Phenylpropanolamine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/chemspider/25082 http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/drugbank/DB00397 http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/kegg-compound/C07911 http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/pubchem-compound/26934 http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/pubchem-substance/46508087 http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/pharmgkb/PA164748965 http://linked.opendata.cz/resource/drugbank/drug/DB00397/identifier/wikipedia/Phenylpropanolamine
http://linked.open...mechanismOfAction	Phenylpropanolamine acts directly on alpha- and, to a lesser degree, beta-adrenergic receptors in the mucosa of the respiratory tract. Stimulation of alpha-adrenergic receptors produces vasoconstriction, reduces tissue hyperemia, edema, and nasal congestion, and increases nasal airway patency. PPA indirectly stimulates beta-receptors, producing tachycardia and a positive inotropic effect. (en)
http://linked.open...drugbank/packager	Corvit Pharmaceuticals DHHS Program Support Center Supply Service Center Direct Dispensing Inc. Duramed Econolab Inc. American Regent APP Pharmaceuticals APPD A-S Medication Solutions LLC Cardinal Health JHP Pharmaceuticals LLC Luitpold Pharmaceuticals Inc. Pharmaceutical Utilization Management Program VA Inc. PD-Rx Pharmaceuticals Inc. Parke davis div warner lambert co Bayer Healthcare Berlex Labs Astellas Pharma Inc. Ben Venue Laboratories Inc. Bristol-Myers Squibb Co. Amerisource Health Services Corp. Innovative Manufacturing and Distribution Services Inc. Breckenridge Pharmaceuticals Bristol-Myers Squibb Co. C.O. Truxton Inc. Carlisle Laboratories Inc. Century Pharmaceuticals Inc. Chattem Chemicals Inc. Physicians Total Care Inc. Prescript Pharmaceuticals Generics Puerto Rico Inc. Bristol-Myers Squibb Co. Golden State Medical Supply Inc. H and H Laboratories Hi Tech Pharmacal Co. Inc. Boehringer ingelheim pharmaceuticals inc Astrazeneca lp Dey lp Kraft Pharmaceutical Co. Inc. Lark Pharmaceuticals Inc. Llorens Pharmaceutical Long Island Pharmacal Kaiser Foundation Hospital Major Pharmaceuticals Murfreesboro Pharmaceutical Nursing Supply Pharmaceutical Utilization Management Program VA Inc. Murfreesboro Pharmaceutical Nursing Supply Prometic Pharma Inc. Qualitest APP Pharmaceuticals Baxter International Inc. Bedford Labs Seatrace Pharmaceuticals Inc. Ben Venue Laboratories Inc. Bristol-Myers Squibb Co. Cardinal Health
http://linked.open.../drugbank/synonym	Norephedrine (en) 2-amino-1-phenylpropan-1-ol (en) Fenilpropanolamina (en) Norephedrin (en) PPA (en) Phenylpropanolamin (en) Phenylpropanolaminum (en) Phénylpropanolamine (en) β-hydroxyamphetamine) (en)
http://linked.open...drugbank/toxicity	May induce ventricular extrasystoles and short paroxysms of ventricular tachycardia, a sensation of fullness in the head and tingling of the extremities; LD<sub>50</sub>=1490mg/kg (orally in rat) (en)
http://linked.open...k/foodInteraction	Limit caffeine intake. (en) Take without regard to meals. (en)
http://linked.open.../drugbank/mixture	Alka Seltzer Plus Cold Medicine Evt Bronchodex D Cap Bronchosirum Pour Enfants Caldomine DH Centracol DM Chlor Tripolon Decongest Cold & Allergy Cold & Allergy Relief Cold Decongestant Long Acting Cold Relief Cold Relief DM Coltalin Tablet Contac Cold Capsules Contac Cold Extra Strength Capsules Contac Cough Cold and Flu Caplets Contact C

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