About: Carisoprodol

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202) (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B422A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B422B-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Toth PP, Urtis J: Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. Clin Ther. 2004 Sep;26(9):1355-67. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15530999 # Chou R, Peterson K, Helfand M: Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review. J Pain Symptom Manage. 2004 Aug;28(2):140-75. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15276195 # Littrell RA, Hayes LR, Stillner V: Carisoprodol (Soma): a new and cautious perspective on an old agent. South Med J. 1993 Jul;86(7):753-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8322081 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	8 hours (en)
http://linked.open...ugbank/indication	For the relief of discomfort associated with acute, painful, musculoskeletal conditions. (en)
http://linked.open...bank/manufacturer	Corepharma llc Mutual pharmaceutical co inc Pioneer pharmaceuticals inc Sandoz inc Sun pharmaceutical industries ltd Vintage pharmaceuticals inc Eli lilly and co Mylan pharmaceuticals inc Sandoz inc Bristol-Myers Squibb Co. Able laboratories inc Actavis totowa llc J T Baker Aurobindo pharma ltd Bristol laboratories inc div bristol myers co
sameAs	Carisoprodol
Title	Carisoprodol (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/chebi/3419 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/chemspider/2478 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/drugbank/DB00395 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/kegg-compound/C07927 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/kegg-drug/D00768 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/national-drug-code-directory/12634-437-91 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/pubchem-compound/2576 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/pubchem-substance/46506377 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/pharmgkb/PA448809 http://linked.opendata.cz/resource/drugbank/drug/DB00395/identifier/wikipedia/Carisoprodol
http://linked.open...mechanismOfAction	Carisoprodol is a central nervous system depressant that acts as a sedative and skeletal muscle relaxant. Rather than acting directly on skeletal muscle, carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. Its exact mechanism of action is not yet known. (en)
http://linked.open...drugbank/packager	Bio Technology General Ltd. Bristol-Myers Squibb Co. BTG Pharmaceuticals Corp. Ebewe Pharma Eli Lilly & Co. Advanced Pharmaceutical Services Inc. Amerisource Health Services Corp. Allergy Laboratories Inc. A-S Medication Solutions LLC American Regent A-S Medication Solutions LLC Ben Venue Laboratories Inc. C.O. Truxton Inc. Pharmaceutical Utilization Management Program VA Inc. Dispensing Solutions Pfizer Inc. Eon Labs Hope Pharmaceuticals Sandoz Lake Erie Medical and Surgical Supply Major Pharmaceuticals Mallinckrodt Inc. Genentech inc Medvantx Inc. Cangene corp Sandoz Novartis AG Eli lilly and co Novo nordisk inc Patheon Inc. Emd serono inc Lg life sciences ltd Physicians Total Care Inc. Preferred Pharmaceuticals Inc. Prepackage Specialists Prepak Systems Inc. Aidarex Pharmacuticals LLC Amerisource Health Services Corp. Apotheca Inc. A-S Medication Solutions LLC Aurobindo Pharma Ltd. Blenheim Pharmacal Abbott Laboratories Ltd. Astrazeneca pharmaceuticals lp Carlisle Laboratories Inc. Ivax pharmaceuticals inc sub teva pharmaceuticals usa Corepharma LLC Darby Dental Supply Co. Inc. Direct Dispensing Inc. Dispensing Solutions Alphapharm pty ltd Barr laboratories inc Eon Labs Ivax pharmaceuticals inc sub teva pharmaceuticals usa H and H Laboratories H.J. Harkins Co. Inc. Heartland Repack Services LLC Innoviant Pharmacy Inc.
http://linked.open...outeOfElimination	Carisoprodol is eliminated by both renal and non-renal routes. (en)
http://linked.open.../drugbank/synonym	Carisoprodol (en) Carisoprodate (en) Isomeprobamate (en) Isobamate (en) Isopropylmeprobamate (en)

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