About: Dydrogesterone     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation. [PubChem] (en)
http://linked.open...generalReferences
  • # "Link":http://www.patient.co.uk/showdoc/30003042/ (en)
http://linked.open...gy/drugbank/group
  • approved (en)
  • withdrawn (en)
http://linked.open...drugbank/halfLife
  • Dydrogesterone: 5-7 hours, 20-dihydrodydrogesterone (DHD) metabolite: 14-17 hours (en)
http://linked.open...ugbank/indication
  • Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history of habitual abortions. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Dydrogesterone (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Dydrogesterone is a progestogen that works by regulating the healthy growth and normal shedding of the womb lining by acting on progesterone receptors in the uterus. (en)
http://linked.open.../drugbank/synonym
  • Dydrogesterone (en)
  • Gestatron (en)
  • 10alpha-Isopregnenone (en)
  • Hydrogesterone (en)
  • Hydrogestrone (en)
  • Isopregnenone (en)
  • (9β,10α)-pregna-4,6-diene-3,20-dione (en)
  • 6-Dehydro-retro-progesterone (en)
  • 9β,10α-pregna-4,6-diene-3,20-dione (en)
  • Didrogesterona (en)
  • Didrogesterone (en)
  • Dydrogesterona (en)
  • Dydrogesteronum (en)
  • Dydrogestérone (en)
  • Retro-6-dehydroprogesterone (en)
  • delta(6)-Retroprogesterone (en)
  • delta(Sup 6)-retroprogesterone (en)
http://linked.open...drugbank/toxicity
  • No serious or unexpected toxicity has been observed with dydrogesterone. In acute toxicity studies, the LD50 doses in rats exceeded 4,640mg/kg for the oral route. (en)
http://linked.open.../drugbank/mixture
http://linked.open...ynthesisReference
  • Reerink, E.H., Westerhof, P. and Scholer, H.F.L.; U.S. Patent 3,198,792; assigned to North American Philips Company, Inc. (en)
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • Rapidly absorbed in the gastrointestinal tract with a bioavailability of 28%. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 152-62-5 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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