About: Cetirizine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B5AB5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5AB6-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5AB7-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5AB8-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5AB9-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5ABA-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B5ABB-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	8.3 hours (en)
http://linked.open...ugbank/indication	For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria (en)
http://linked.open...bank/manufacturer	Banner pharmacaps inc Actavis mid atlantic llc Amneal pharmaceuticals Apotex inc Aurobindo pharma ltd Cypress pharmaceutical inc Dr reddys laboratories ltd PD-Rx Pharmaceuticals Inc. Perrigo Co. Pharmaceutical Association Pharmaceutical Utilization Management Program VA Inc. Bedford Labs Ben Venue Laboratories Inc. Bristol-Myers Squibb Co. Hospira Inc. Mead Johnson and Co. Caraco pharmaceutical laboratories ltd Prepak Systems Inc. Pfizer inc Abbott laboratories Abbott laboratories hosp products div App pharmaceuticals llc Baxter healthcare corp anesthesia and critical care Baxter healthcare corp anesthesia and critical care Baxter healthcare corp Gd searle llc Apothecon inc div bristol myers squibb International medication system
sameAs	Cetirizine
Title	Cetirizine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/bindingdb/22890 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/chebi/3561 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/chemspider/2577 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/drugbank/DB00341 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/guide-to-pharmacology/1222 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/iuphar/1222 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/kegg-compound/C07778 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/national-drug-code-directory/16714-271-02 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/pubchem-compound/2678 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/pubchem-substance/46508368 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/pharmgkb/PA448905 http://linked.opendata.cz/resource/drugbank/drug/DB00341/identifier/wikipedia/Cetirizine
http://linked.open...mechanismOfAction	Cetirizine competes with histamine for binding at H<sub>1</sub>-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The low incidence of sedation can be attributed to reduced penetration of cetirizine into the CNS as a result of the less lipophilic carboxyl group on the ethylamine side chain. (en)
http://linked.open...drugbank/packager	Actavis Group Advanced Pharmaceutical Services Inc. Apotex Inc. Apotheca Inc. AQ Pharmaceuticals Inc. App pharmaceuticals llc Aurobindo Pharma Ltd. Bryant Ranch Prepack Caraco Pharmaceutical Labs Sandoz CVS Pharmacy Cypress Pharmaceutical Inc. DHHS Program Support Center Supply Service Center Caraco pharmaceutical laboratories ltd Naska pharmacal co inc div rugby darby group cosmetics Corepharma llc Doctor Reddys Laboratories Ltd. Dorx LLC H.J. Harkins Co. Inc. Equaline Vitamins Gm Pharmaceuticals Inc. Golden State Medical Supply Inc. Greenstone LLC A-S Medication Solutions LLC Bryant Ranch Prepack Cardinal Health Direct Dispensing Inc. Diversified Healthcare Services Inc. Abraxis BioScience Inc. Accord Healthcare APP Pharmaceuticals Pfizer Inc. Bedford Labs Pfizer Inc. Bristol-Myers Squibb Co. Ebewe Pharma Ethex Corp. Fresenius Kabi AB Hospira Inc. Intas Pharmaceuticals Ltd. Sandoz Mckesson Corp. McNeil Laboratories Sandoz Medique Products

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