| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - Conjugated estrogens, a mixture of the water-soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids, may be derived from pregnant equine urine or yam and soy plants. Estrogens are important in the development and maintenance of the female reproductive system and secondary sex characteristics. (en)
|
| http://linked.open...y/drugbank/dosage
| |
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...drugbank/halfLife
| |
| http://linked.open...ugbank/indication
| - For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only) (en)
|
| http://linked.open...bank/manufacturer
| |
| sameAs
| |
| Title
| - Conjugated Estrogens (en)
|
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - Estrogens enter the cells of responsive tissues (e.g., female organs, breasts, hypothalamus, pituitary) where they interact with a protein receptor, subsequently increasing the rate of synthesis of DNA, RNA, and some proteins. Estrogens decrease the secretion of gonadotropin-releasing hormone by the hypothalamus, reducing the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open...y/drugbank/patent
| |
| http://linked.open...outeOfElimination
| - Estradiol, estrone, and estriol are excreted in the urine, along with glucuronide and sulfate conjugates. Exogenous estrogens are metabolized in the same manner as endogenous estrogens. (en)
|
| http://linked.open.../drugbank/synonym
| - Estrogens (en)
- Conestoral (en)
- Evex (en)
- Hyhorin (en)
- Morestin (en)
- Premarin (en)
- 17-Oxoestra-1,3,5(10)-trien-3-yl sodium sulfate (en)
- Estrogenic substances (conjugated) (en)
- Estrone sodium sulfate (en)
- Estrone sulfate sodium (en)
- Estrone-3-sulfate sodium salt (en)
- Oestrone-3-sulphate sodium salt (en)
- Sodium estrone 3-sulfate (en)
|
| http://linked.open...drugbank/toxicity
| |
| http://linked.open.../drug/hasAHFSCode
| |
| http://linked.open...k/foodInteraction
| |
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