About: Dihomo-gamma-linolenic acid

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About: Dihomo-gamma-linolenic acid Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. [PubChem] (en)
http://linked.open...gy/drugbank/group	approved (en) nutraceutical (en)
http://linked.open...ugbank/indication	For nutritional supplementation, also for treating dietary shortage or imbalance (en)
sameAs	Dihomo-gamma-linolenic acid
Title	Dihomo-gamma-linolenic acid (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/chemspider/4444199 http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/drugbank/DB00154 http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/kegg-compound/C03242 http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/pdb/LAX http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/pubchem-compound/5280581 http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/pubchem-substance/46508866 http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/chebi/53486 http://linked.opendata.cz/resource/drugbank/drug/DB00154/identifier/pharmgkb/PA164743249
http://linked.open...mechanismOfAction	DHLA (or DGLA) is a precursor in the synthesis of prostaglandin E1 (PGE1) as well as the series-3 prostaglandins. It also serves as a precursor in the synthesis of eicosapentaenoic acid (EPA). EPA is a precursor of the series-3 prostaglandins, the series-5 leukotrienes and the series-3 thromboxanes. These eicosanoids have anti-thrombogenic, anti-inflammatory and anti-atherogenic properties. PGE1 inhibits platelet aggregation and has a vasodilation action. DHLA has also been shown to reduce the production/activity of tumor necrosis factor alpha. (en)
http://linked.open.../drugbank/synonym	gamma-Homolinolenic acid (en) (Z,Z,Z)-8,11,14-Eicosatrienoic acid (en) 8,11,14-Eicosatrienoic Acid (en) DGLA (en) Homo-gamma-linolenic acid (en) (8Z,11Z,14Z)-Icosatrienoic acid (en) (Z,Z,Z)-8,11,14-Icosatrienoate (en) (Z,Z,Z)-8,11,14-Icosatrienoic acid (en) 20:3, n-6,9,12 all-cis (en) 8c,11c,14c-Eicosatriensaeure (en) 8c,11c,14c-eicosatrienoic acid (en) C20:3, n-6,9,12 all-cis (en) Dihomo-γ-linolenic acid (en) Homo-gamma-linolensaeure (en) all-cis-8,11,14-eicosatrienoic acid (en) all-cis-8,11,14-icosatrienoic acid (en) all-cis-Eicosa-8,11,14-triensaeure (en) all-cis-eicosa-8,11,14-trienoic acid (en) all-cis-icosa-8,11,14-trienoic acid (en) cis,cis,cis-8,11,14-eicosatrienoic acid (en) eicosa-8Z,11Z,14Z-trienoic acid (en)
http://linked.open...ynthesisReference	Hiroshi Kawashima, "Process for production of dihomo-gamma-linolenic acid and lipid containing same." U.S. Patent US20010021522, issued September 13, 2001. (en)
foaf:page	http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/gam_0120.shtml
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http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	1783-84-2 (en)
http://linked.open...drugbank/category	(en)
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