About: Creatine

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About: Creatine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
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http://linked.open...gbank/description	An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. [PubChem] (en)
http://linked.open...generalReferences	# Burke DG, Chilibeck PD, Parise G, Tarnopolsky MA, Candow DG: Effect of alpha-lipoic acid combined with creatine monohydrate on human skeletal muscle creatine and phosphagen concentration. Int J Sport Nutr Exerc Metab. 2003 Sep;13(3):294-302. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/14669930 # Dangott B, Schultz E, Mozdziak PE: Dietary creatine monohydrate supplementation increases satellite cell mitotic activity during compensatory hypertrophy. Int J Sports Med. 2000 Jan;21(1):13-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10683092 # Hespel P, Op't Eijnde B, Van Leemputte M, Urso B, Greenhaff PL, Labarque V, Dymarkowski S, Van Hecke P, Richter EA: Oral creatine supplementation facilitates the rehabilitation of disuse atrophy and alters the expression of muscle myogenic factors in humans. J Physiol. 2001 Oct 15;536(Pt 2):625-33. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11600695 # Hultman E, Soderlund K, Timmons JA, Cederblad G, Greenhaff PL: Muscle creatine loading in men. J Appl Physiol. 1996 Jul;81(1):232-7. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8828669 # Juhn M: Popular sports supplements and ergogenic aids. Sports Med. 2003;33(12):921-39. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12974658 (en)
http://linked.open...gy/drugbank/group	approved (en) nutraceutical (en)
http://linked.open...drugbank/halfLife	3 hours (en)
http://linked.open...ugbank/indication	For nutritional supplementation, also for treating dietary shortage or imbalance (en)
sameAs	Creatine
Title	Creatine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/chebi/16919 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/chemspider/566 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/drugbank/DB00148 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/kegg-compound/C00300 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/pdb/CRN http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/pubchem-compound/586 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/pubchem-substance/46504868 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/pharmgkb/PA164778930 http://linked.opendata.cz/resource/drugbank/drug/DB00148/identifier/wikipedia/Creatine
http://linked.open...mechanismOfAction	In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosphocreatine (PCr). Phosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source for short term ATP needs prior to oxidative phosphorylation. (en)
http://linked.open...drugbank/packager	National Vitamin Company Advanced Pharmaceutical Services Inc. Akorn Inc.
http://linked.open.../drugbank/synonym	Creatine (en) Creatin (en) Kreatin (en) (alpha-Methylguanido)acetic acid (en) N-Amidinosarcosine (en) N-Methyl-N-guanylglycine (en) ((amino(Imino)methyl)(methyl)amino)acetic acid (en) (N-methylcarbamimidamido)acetic acid (en) (α-methylguanido)acetic acid (en) Methylglycocyamine (en) N-(aminoiminomethyl)-N-methylglycine (en) N-Carbamimidoyl-N-methylglycine (en) N-[(e)-AMINO(imino)methyl]-N-methylglycine (en) alpha-Methylguanidino acetic acid (en)
http://linked.open...ynthesisReference	Stefan Weiss, Helmut Krommer, "Process for the preparation of a creatine or creatine monohydrate." U.S. Patent US5719319, issued September, 1963. (en)
foaf:page	http://www.drugs.com/creatine.html http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/cre_0086.shtml
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http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	57-00-1 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Creatine powder Cytotine 1.5 g/15 ml liquid Creatine monohydrate powder
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