| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. [PubChem] (en)
|
| http://linked.open...gy/drugbank/group
| - approved (en)
- nutraceutical (en)
|
| http://linked.open...ugbank/indication
| - Used as a natural moisturizing agent in some cosmetics and skin care products. (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of L-serine to glycine by serine hydroxymethyltransferase results in the formation of the one-carbon units necessary for the synthesis of the purine bases, adenine and guanine. These bases when linked to the phosphate ester of pentose sugars are essential components of DNA and RNA and the end products of energy producing metabolic pathways, ATP and GTP. In addition, L-serine conversion to glycine via this same enzyme provides the one-carbon units necessary for production of the pyrimidine nucleotide, deoxythymidine monophosphate, also an essential component of DNA. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open.../drugbank/synonym
| - L-Serine (en)
- (S)-2-Amino-3-hydroxypropanoic acid (en)
- (S)-Serine (en)
- L-(-)-Serine (en)
- L-3-Hydroxy-2-aminopropionic acid (en)
- L-Ser (en)
- Serine (en)
- S (en)
- (2S)-2-amino-3-Hydroxypropanoic acid (en)
- (S)-(-)-Serine (en)
- (S)-(−)-serine (en)
- (S)-alpha-Amino-beta-hydroxypropionic acid (en)
- L-(−)-serine (en)
- L-2-Amino-3-hydroxypropionic acid (en)
- L-3-Hydroxy-alanine (en)
- L-Serin (en)
- Ser (en)
- beta-Hydroxy-L-alanine (en)
- beta-Hydroxyalanine (en)
|
| http://linked.open...ynthesisReference
| - Kenichi Ishiwata, Nobuyoshi Makiguichi, Hideki Kawashima, Tadashi Suzuki, Masami Imadegawa, "Method of producing L-serine." U.S. Patent US4782021, issued August, 1973. (en)
|
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
| http://linked.open.../Molecular-Weight
| |
| http://linked.open...noisotopic-Weight
| |
| http://linked.open...y/drugbank/SMILES
| |
| http://linked.open.../Water-Solubility
| |
| http://linked.open...ogy/drugbank/logP
| |
| http://linked.open...ogy/drugbank/logS
| |
| http://linked.open...logy/drugbank/pKa
| |
| http://linked.open...nd-Acceptor-Count
| |
| http://linked.open...-Bond-Donor-Count
| |
| http://linked.open...drugbank/InChIKey
| |
| http://linked.open...urface-Area--PSA-
| |
| http://linked.open...nk/Polarizability
| |
| http://linked.open...bank/Refractivity
| |
| http://linked.open...atable-Bond-Count
| |
| http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
|
| http://linked.open...casRegistryNumber
| |
| http://linked.open...drugbank/category
| |
| http://linked.open...gbank/containedIn
| |
| http://linked.open...k/Bioavailability
| |
| http://linked.open...bank/Ghose-Filter
| |
| http://linked.open...nk/MDDR-Like-Rule
| |
| http://linked.open...ank/Melting-Point
| |
| http://linked.open...k/Number-of-Rings
| |
| http://linked.open...siological-Charge
| |
| http://linked.open...bank/Rule-of-Five
| |
| http://linked.open...tional-IUPAC-Name
| |
| http://linked.open...strongest-acidic-
| |
| http://linked.open...-strongest-basic-
| |
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