About: Abarelix

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market. (en)
http://linked.open...gy/drugbank/group	approved (en) withdrawn (en) investigational (en)
http://linked.open...drugbank/halfLife	13.2 ± 3.2 days (en)
http://linked.open...ugbank/indication	For palliative treatment of advanced prostate cancer. (en)
http://linked.open...bank/manufacturer	Direct Dispensing Inc.
sameAs	Abarelix
Title	Abarelix (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/bindingdb/50102442 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/drugbank/DB00106 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/guide-to-pharmacology/1188 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/iuphar/1188 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/kegg-drug/D02738 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/chebi/337298 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/pharmgkb/PA164754915 http://linked.opendata.cz/resource/drugbank/drug/DB00106/identifier/wikipedia/Abarelix
http://linked.open...mechanismOfAction	Abarelix binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion. (en)
http://linked.open...drugbank/packager	Baxter International Inc. Pharmaceutical Utilization Management Program VA Inc.
http://linked.open...y/drugbank/patent	http://linked.opendata.cz/resource/drugbank/patent/5968895 http://linked.opendata.cz/resource/drugbank/patent/6423686
http://linked.open...drugbank/toxicity	The maximum tolerated dose of abarelix has not been determined. The maximum dose used in clinical studies was 150 mg. There have been no reports of accidental overdose with abarelix. (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/10-00%20
http://linked.open...nk/proteinBinding	96-99% (en)
foaf:page	http://www.drugs.com/cdi/abarelix.html http://www.rxlist.com/cgi/generic/plenaxis.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B45AD-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B45AC-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Abarelix
http://linked.open...ugbank/absorption	Following IM administration of 100 mg, abarelix is absorbed slowly with a mean peak concentration of 43.4 ng/mL observed approximately 3 days after the injection. (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	183552-38-7 (en)
http://linked.open...drugbank/category	(en)

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