About: Pegademase bovine

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About: Pegademase bovine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Bovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended serum half life. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B42B5-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	#Lexicomp Online (2014). Pegademase Bovine. Available at:http://online.lexi.com/lco/action/doc/retrieve/docid/patch_f/7443#f_pharmacology-and-pharmacokinetics [Accessed 12 Nov. 2014]. (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	plasma adenosine deaminase elimination half-life is 3 to >6 days (en)
http://linked.open...ugbank/indication	For treatment of adenosine deaminase deficiency (en)
http://linked.open...bank/manufacturer	Bayer Healthcare
sameAs	Pegademase bovine
Title	Pegademase bovine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00061/identifier/drugbank/DB00061 http://linked.opendata.cz/resource/drugbank/drug/DB00061/identifier/genbank/AF280603 http://linked.opendata.cz/resource/drugbank/drug/DB00061/identifier/national-drug-code-directory/57665-001-01 http://linked.opendata.cz/resource/drugbank/drug/DB00061/identifier/uniprotkb/P56658 http://linked.opendata.cz/resource/drugbank/drug/DB00061/identifier/pharmgkb/PA450831
http://linked.open...mechanismOfAction	Pegademase converts adenosine (toxic) to inosine (less toxic) by deamination. It also converts 2'-deoxyadenosine to 2'-deoxyinosine via deamination. (en)
http://linked.open...drugbank/packager	A-S Medication Solutions LLC Atlantic Biologicals Corporation
http://linked.open.../drugbank/synonym	Adenosine aminohydrolase (en) Adenosine deaminase (en)
http://linked.open...ynthesisReference	Paul Skonezny, "Process for preparing dideoxyinosine using adenosine deaminase enzyme." U.S. Patent US20040175804, issued September 09, 2004. (en)
foaf:page	http://www.drugs.com/cdi/pegademase-bovine.html http://www.rxlist.com/cgi/generic2/pegademase.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B42B9-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B42B8-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Time to peak for plasma adenosine deaminase is 2 to 3 days (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	9026-93-1 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Adagen 250 unit/ml vial
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B42B6-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B42B7-363D-11E5-9242-09173F13E4C5

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