About: Cetrorelix

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About: Cetrorelix Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released. Cetrorelix does not allow the premature release of these eggs to occur. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B41C3-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B41C4-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en) investigational (en)
http://linked.open...drugbank/halfLife	~62.8 hours (en)
http://linked.open...ugbank/indication	For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation (en)
http://linked.open...bank/manufacturer	Emd serono inc
sameAs	Cetrorelix
Title	Cetrorelix (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00050/identifier/chebi/59224 http://linked.opendata.cz/resource/drugbank/drug/DB00050/identifier/drugbank/DB00050 http://linked.opendata.cz/resource/drugbank/drug/DB00050/identifier/kegg-drug/D01685 http://linked.opendata.cz/resource/drugbank/drug/DB00050/identifier/national-drug-code-directory/44087-1225-1 http://linked.opendata.cz/resource/drugbank/drug/DB00050/identifier/pharmgkb/PA164764506 http://linked.opendata.cz/resource/drugbank/drug/DB00050/identifier/wikipedia/Cetrorelix
http://linked.open...mechanismOfAction	Cetrorelix binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion. It competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner. (en)
http://linked.open...drugbank/packager	Baxter International Inc. EMD Canada Inc. Murfreesboro Pharmaceutical Nursing Supply
http://linked.open...y/drugbank/patent	http://linked.opendata.cz/resource/drugbank/patent/2115943 http://linked.opendata.cz/resource/drugbank/patent/5198533 http://linked.opendata.cz/resource/drugbank/patent/6319192
http://linked.open...outeOfElimination	Following subcutaneous administration of 10 mg cetrorelix to males and females, only unchanged cetrorelix was detected in urine. (en)
http://linked.open.../drugbank/synonym	Cetrorelixum (en)
http://linked.open...umeOfDistribution	* 1.16 L/kg (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/92-00-00
http://linked.open...nk/proteinBinding	86% (en)
http://linked.open...ogy/drugbank/salt	(en)
foaf:page	http://www.drugs.com/cdi/cetrorelix-acetate.html http://www.rxlist.com/cgi/generic2/cetrorelix.htm
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B41C9-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B41CF-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B41CE-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B41CB-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B41CC-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B41CD-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B41C7-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B41C5-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B41C8-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B41C6-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Cetrorelix
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B41D5-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B41D6-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B41D0-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B41D1-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B41D3-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B41D2-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B41D4-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%. (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	120287-85-6 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...rugbank/clearance	* 1.28 ml/min·kg [adult healthy female with 3 mg single SC administration] (en)
http://linked.open...gbank/containedIn	Cetrotide 0.25 mg kit Cefzil 250 mg/5ml Suspension 100ml Bottle
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B41DB-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B41DD-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B41DE-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B41DA-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B41D9-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B41DC-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B41CA-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B41D7-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B41D8-363D-11E5-9242-09173F13E4C5

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