About: OspA lipoprotein

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant. (en)
http://linked.open...gy/drugbank/group	approved (en) withdrawn (en)
http://linked.open...drugbank/halfLife	1.2 hours (mammalian reticulocytes, in vitro). (en)
http://linked.open...ugbank/indication	For prophylactic treatment of Lyme Disease (en)
sameAs	OspA lipoprotein
Title	OspA lipoprotein (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/drugbank/DB00045 http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/genbank/X16467 http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/uniprotkb/P14013 http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/pharmgkb/PA164743058
http://linked.open...mechanismOfAction	OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks. (en)
http://linked.open.../drugbank/synonym	Outer surface protein A precursor (en)
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B4173-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B4172-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...drugbank/category	(en)
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B4170-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B4171-363D-11E5-9242-09173F13E4C5

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