About: Scopolamine

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	An alkaloid from Solanaceae, especially Datura metel L. and Scopola carniolica. Scopolamine and its quaternary derivatives act as antimuscarinics like atropine, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in urinary incontinence, in motion sickness, as an antispasmodic, and as a mydriatic and cycloplegic. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B56B9-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Putcha L, Cintron NM, Tsui J, Vanderploeg JM, Kramer WG: Pharmacokinetics and oral bioavailability of scopolamine in normal subjects. Pharm Res. 1989 Jun;6(6):481-5. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/2762223 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	4.5 hours (en)
http://linked.open...ugbank/indication	For the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness. (en)
http://linked.open...bank/manufacturer	A-S Medication Solutions LLC Atlantic Biologicals Corporation
sameAs	Scopolamine
Title	Scopolamine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/bindingdb/50015720 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/chebi/16794 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/drugbank/DB00747 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/guide-to-pharmacology/330 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/iuphar/330 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/kegg-compound/C01851 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/kegg-drug/D00138 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/national-drug-code-directory/0067-4345-04 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/pharmgkb/PA451308 http://linked.opendata.cz/resource/drugbank/drug/DB00747/identifier/wikipedia/Scopolamine
http://linked.open...mechanismOfAction	Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center). (en)
http://linked.open...drugbank/packager	A. Aarons Inc. Adamis Laboratories Advanced Pharmaceutical Services Inc. Alcon Laboratories Alza Corp. Amend Abc holding corp Apotheca Inc. APP Pharmaceuticals Aristos Pharmaceuticals A-S Medication Solutions LLC Atlantic Biologicals Corporation Auriga Pharmaceuticals LLC App pharmaceuticals llc Baxter International Inc. Boca Pharmacal Bradley Pharmaceuticals Inc. Breckenridge Pharmaceuticals Bryant Ranch Prepack Angiodynamics Bioniche Pharma Bioniche pharma usa llc Central Texas Community Health Centers Contract Pharm Cornerstone Pharmacy Corvit Pharmaceuticals Dexo LLC Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Excellium Pharmaceutical Inc. H.J. Harkins Co. Inc. Hawthorn Pharmaceuticals Actavis Group Advanced Pharmaceutical Services Inc. Alphapharm Party Ltd. Amerisource Health Services Corp. Amkas Laboratories Inc. Amneal Pharmaceuticals Apotex Inc. Apotheca Inc. AQ Pharmaceuticals Inc. A-S Medication Solutions LLC Advanced Pharmaceutical Services Inc. Amerisource Health Services Corp. Apotex Inc. AQ Pharmaceuticals Inc. A-S Medication Solutions LLC Bryant Ranch Prepack Cadila Healthcare Ltd. Atlantic Biologicals Corporation Cardinal Health Caremark LLC Cobalt Pharmaceuticals Inc. Biovail laboratories international srl Pharmaceutical Utilization Management Program VA Inc. Actavis elizabeth llc Akorn Inc. Allergan Inc. Amerisource Health Services Corp. Apotex Inc. Apotheca Inc. Ivax pharmaceuticals inc sub teva pharmaceuticals usa APP Pharmaceuticals A-S Medication Solutions LLC Baxter International Inc. Bedford Labs Ben Venue Laboratories Inc. Bryant Ranch Prepack Cardinal Health Corepharma LLC Pharmaceutical Utilization Management Program VA Inc. Direct Dispensing Inc. Dispensing Solutions Actavis Group Apotex Inc.
http://linked.open...outeOfElimination	Less than 10% of the total dose is excreted in the urine as parent and metabolites over 108 hours. (en)
http://linked.open.../drugbank/synonym	Scopolamine (en)

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