About: Acotiamide Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Acotiamide Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Acotiamide Hydrochloride
UMLS_CUI
  • C0915799
CAS_Registry
  • 773092-05-0
FDA_UNII_Code
  • NMW7447A9A
Contributing_Source
  • FDA
Chemical_Formula
  • C21H30N4O5S.ClH.3H2O
Legacy_Concept_Name
  • Acotiamide_hydrochloride
FULL_SYN
  • Acotiamide HydrochloridePTNCI
  • ACOTIAMIDE HYDROCHLORIDEPTFDANMW7447A9A
  • Z-338CNNCI
  • YM443CNNCI
DEFINITION
  • The hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.NCI
code
  • C72222
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
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