About: Mezlocillin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mezlocillin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Mezlocillin
UMLS_CUI
  • C0025893
CAS_Registry
  • 51481-65-3
FDA_UNII_Code
  • OH2O403D1G
Contributing_Source
  • FDA
ALT_DEFINITION
  • Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39505
PDQ_Closed_Trial_Search_ID
  • 39505
Chemical_Formula
  • C21H25N5O8S2
Legacy_Concept_Name
  • Mezlocillin
CHEBI_ID
  • CHEBI:6919
FULL_SYN
  • MezlocillinPTNCI
  • MezlinBRNCI
  • MEZLOCILLINPTFDAOH2O403D1G
DEFINITION
  • A broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. Mezlocillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts the final stage of bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and eventually causing cell lysis.NCI
code
  • C653
sameAs
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