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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Midazolam
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Midazolam
UMLS_CUI
  • C0026056
CAS_Registry
  • 59467-70-8
FDA_UNII_Code
  • R60L0SM5BC
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat anxiety and tension and to relax muscles. It is also being studied in the treatment of nausea and vomiting caused by some cancer treatments. It is a type of benzodiazepine.NCI-GLOSS
Chemical_Formula
  • C18H13ClFN3
Legacy_Concept_Name
  • Midazolam_Base
FULL_SYN
  • MIDAZOLAMPTFDAR60L0SM5BC
  • MidazolamPTNCI
  • midazolamPTNCI-GLOSSCDR0000476308
DEFINITION
  • A short-acting benzodiazepine derivative with an imidazole structure and with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties. Midazolam exerts its effect by binding to the benzodiazepine receptor at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA in the CNS. Midazolam may also interfere with the reuptake of GABA, thereby causing accumulation of GABA in the synaptic cleft.NCI
code
  • C62049
sameAs
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