About: Pegylated Anti-GFR Antibody Fragment     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pegylated Anti-GFR Antibody Fragment
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pegylated Anti-GFR Antibody Fragment
UMLS_CUI
  • C1831765
PDQ_Open_Trial_Search_ID
  • 472077
PDQ_Closed_Trial_Search_ID
  • 472077
Legacy_Concept_Name
  • Pegylated_Anti-GRF_Antibody_Fragment
FULL_SYN
  • Pegylated Anti-GFR Antibody FragmentPTNCI
  • CDP-791CNNCI
DEFINITION
  • A pegylated, cross-linked, humanized divalent-Fab' antibody fragment directed against vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antiangiogenic and antitumor activities. Pegylated anti-GFR antibody fragment binds to and inhibits VEGFR-2, which may inhibit angiogenesis and tumor cell proliferation. Multivalent Fab' antibody fragments may exhibit improved retention and internalization properties compared to their parent IgGs.NCI
code
  • C61438
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