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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ethosuximide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ethosuximide
NSC_Code
  • 64013
UMLS_CUI
  • C0015043
CAS_Registry
  • 77-67-8
FDA_UNII_Code
  • 5SEH9X1D1D
Contributing_Source
  • FDA
Chemical_Formula
  • C7H11NO2
Legacy_Concept_Name
  • Ethosuximide
CHEBI_ID
  • CHEBI:4887
FULL_SYN
  • ETHOSUXIMIDEPTFDA5SEH9X1D1D
  • EthosuximidePTNCI
  • 3-Ethyl-3-methylpyrrolidine-2,5-dioneSNNCI
  • ZarontinBRNCI
DEFINITION
  • A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.NCI
code
  • C47523
sameAs
http://linked.open...y/mesh/hasConcept
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