About: Nasal Type Extranodal NK/T-Cell Lymphoma     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Nasal Type Extranodal NK/T-Cell Lymphoma
equivalentClass
Concept_In_Subset
Semantic_Type
  • Neoplastic Process
Preferred_Name
  • Nasal Type Extranodal NK/T-Cell Lymphoma
UMLS_CUI
  • C0392788
Contributing_Source
  • CDISC
  • CTEP
ALT_DEFINITION
  • A malignant lymphoid neoplasm composed of EBV-positive NK/T cells arranged in an angiocentric pattern.CDISC
ICD-O-3_Code
  • 9719/3
Neoplastic_Status
  • Malignant
Legacy_Concept_Name
  • Nasal_Type_Extranodal_NK_T-Cell_Lymphoma
FULL_SYN
  • Extranodal NK/T-cell lymphoma, nasal typePTCTEP10065855
  • RETICULOSIS, MALIGNANTPTCDISC
  • Nasal Type Extranodal NK/T-Cell LymphomaSYNCITCGA
  • Extranodal NK/T lymphoma-nasalSYCTEP10065855
  • Angiocentric T-Cell LymphomaSYNCI
  • ANGIOCENTRIC T-CELL LYMPHOMASYCDISC
  • Nasal Type Extranodal NK/T-Cell LymphomaPTNCI
  • Extranodal NK/T-Cell Lymphoma, Nasal TypeSYNCI
DEFINITION
  • An aggressive, predominantly extranodal, mature T-cell non-Hodgkin lymphoma. It is characterized by an often angiocentric and angiodestructive cellular infiltrate composed of EBV positive NK/T cells. The nasal cavity is the most common site of involvement. Patients often present with midfacial destructive lesions (lethal midline granuloma). The disease may disseminate rapidly to various anatomic sites including the gastrointestinal tract, skin, testis, and cervical lymph nodes. It is also known as angiocentric T-cell lymphoma. The term "polymorphic reticulosis" has been widely used to describe the morphologic changes seen in this type of lymphoma. However, the latter term may also apply to lymphomatoid granulomatosis, which is an angiocentric and angiodestructive EBV positive B-cell lymphoproliferative disorder.NCI
code
  • C4684
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