About: Promethazine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Promethazine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Promethazine Hydrochloride
NSC_Code
  • 231688
UMLS_CUI
  • C0591971
CAS_Registry
  • 58-33-3
FDA_UNII_Code
  • R61ZEH7I1I
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39567
PDQ_Closed_Trial_Search_ID
  • 39567
Chemical_Formula
  • C17H20N2S.HCl
Legacy_Concept_Name
  • Promethazine_Hydrochloride
CHEBI_ID
  • CHEBI:8462
FULL_SYN
  • N-(2-Dimethylaminopropyl-1)phenothiazine HydrochlorideSNNCI
  • Promethazine HydrochloridePTDCP01024
  • Promethazine HydrochloridePTNCI
  • RemsedBRNCI
  • AnerganBRNCI
  • Zipan-50BRNCI
  • PROMETHAZINE HYDROCHLORIDEPTFDAR61ZEH7I1I
  • ProviganBRNCI
  • PhenerganBRNCI
  • Promethazine HClPTDCP30446
DEFINITION
  • The hydrochloride salt form of promethazine, a phenothiazine derivative with antihistaminic, sedative and antiemetic properties. Promethazine hydrochloride selectively blocks peripheral H1 receptors thereby diminishing the effects of histamine on effector cells. Promethazine hydrochloride also blocks the central histaminergic receptors, thereby depressing the reticular system causing sedative and hypnotic effects. In addition, promethazine hydrochloride also has centrally acting anticholinergic properties and probably mediates nausea and vomiting by acting on the medullary chemoreceptive trigger zone.NCI
code
  • C45907
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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