About: Protein Phosphatase 2A     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Protein Phosphatase 2A
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Protein Phosphatase 2A
UMLS_CUI
  • C1704708
Legacy_Concept_Name
  • Protein_Phosphatase_2A_Complex
FULL_SYN
  • Protein Phosphatase 2APTNCI
  • PP2ASYNCI
DEFINITION
  • PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Combinations of different subunit isoforms can generate many forms of PP2A, which may differ in substrate specificity, subcellular localization, or tissue specific expression.NCI
code
  • C42582
sameAs
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