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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Baclofen
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Baclofen
NSC_Code
  • 329137
UMLS_CUI
  • C0699999
CAS_Registry
  • 1134-47-0
Accepted_Therapeutic_Use_For
  • Cerebral Spasticity, Chronic Spasticity
FDA_UNII_Code
  • H789N3FKE8
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat certain types of muscle spasms and is being studied in the treatment of liver cancer. Baclofen relaxes muscles by blocking certain nerve receptors in the spinal cord. It is a type of antispasmodic.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 560777
PDQ_Closed_Trial_Search_ID
  • 560777
Chemical_Formula
  • C10H12ClNO2
Legacy_Concept_Name
  • Baclofen
CHEBI_ID
  • CHEBI:2972
FULL_SYN
  • BACLOFENPTFDAH789N3FKE8
  • beta-(Aminomethyl)-4-chlorobenzenepropanoic AcidSNNCI
  • KemstroPTNCI-GLOSSCDR0000593095
  • BA34647CNNCI
  • 4-Amino-3-(4-chlorophenyl)-butanoic AcidSNNCI
  • KemstroBRNCI
  • baclofenPTNCI-GLOSSCDR0000561430
  • LioresalPTNCI-GLOSSCDR0000593094
  • BaclofenPTNCI
  • GablofenBRNCI
  • LioresalBRNCI
  • BaclofenPTDCP00757
DEFINITION
  • A synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission. (NCI04)NCI
code
  • C28858
sameAs
http://linked.open...y/mesh/hasConcept
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