About: Tucotuzumab Celmoleukin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tucotuzumab Celmoleukin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Tucotuzumab Celmoleukin
UMLS_CUI
  • C1721369
CAS_Registry
  • 339986-90-2
In_Clinical_Trial_For
  • Renal Cell Carcinoma and Refractory Epithelial Carcinoma.
FDA_UNII_Code
  • 4ON7FF680U
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 456358
PDQ_Closed_Trial_Search_ID
  • 456358
Legacy_Concept_Name
  • KSA-Interleukin-2_Fusion_Protein
FULL_SYN
  • huKS-IL2 Fusion ProteinSYNCI
  • Tucotuzumab CelmoleukinPTNCI
  • TUCOTUZUMAB CELMOLEUKINPTFDA4ON7FF680U
  • KSA-interleukin-2SYNCI
  • KSA-IL-2ABNCI
  • EMD 273066CNNCI
  • EMD-273066CNNCI
  • KSA-Interleukin-2 Fusion ProteinSYNCI
DEFINITION
  • A recombinant fusion protein comprised of a human monoclonal antibody directed against the epithelial cell adhesion molecule (EpCAM or KS) linked to an active interleukin-2 (IL2) molecule with potential antineoplastic activity. Tucotuzumab Celmoleukin recognizes and binds to EpCAM, a cell surface epithelial protein that is expressed on a wide variety of cancer cells, thereby concentrating IL2 in EpCAM-expressing tumor tissue. Subsequently, the localized IL2 moiety of the fusion protein may stimulate a cytotoxic T-cell antitumor immune response.NCI
code
  • C2630
http://linked.open...y/mesh/hasConcept
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 33 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software