About: Cytochrome P450 3A4

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Attributes	Values
rdf:type	Class
rdfs:label	Cytochrome P450 3A4
equivalentClass	nodeID://b631778
OMIM_Number	124010
Semantic_Type	Amino Acid, Peptide, or Protein Enzyme
Preferred_Name	Cytochrome P450 3A4
UMLS_CUI	C1142644
Legacy_Concept_Name	Cytochrome-P450-3A4
FULL_SYN	Taurochenodeoxycholate 6-Alpha-HydroxylaseSYNCI EC 1.14.13.-SYNCI EC 1.14.13.32SYNCI EC 1.14.13.67SYNCI EC 1.14.13.97SYNCI Quinine 3-MonooxygenaseSYNCI Albendazole SulfoxidaseSYNCI Cytochrome P450 Nifedipine OxidaseSYNCI Cytochrome P450, Subfamily IIIA, Polypeptide 4SYNCI Albendazole MonooxygenaseSYNCI Steroid-Inducible P450-IIISYNCI P450, FAMILY IIISYNCI P450-III, Steroid InducibleSYNCI P450-III, Steroid-InducibleSYNCI CYP3A4SYNCI Nifedipine OxidaseSYNCI Glucocorticoid-Inducible P450SYNCI Cytochrome P450 3A4PTNCI Cytochrome P450 3A3SYNCI Cytochrome P450PCN1SYNCI Cytochrome P450 HLpSYNCI Cytochrome P450, Subfamily IIIA (Niphedipine Oxidase), Polypeptide 3SYNCI Cytochrome P450, Subfamily IIIA (Niphedipine Oxidase), Polypeptide 4SYNCI P450-3A4SYNCI CYPIIIA3SYNCI CYPIIIA4SYNCI Cytochrome P450-PCN1SYNCI Cytochrome P450 NF-25SYNCI
Swiss_Prot	P08684
DEFINITION	Cytochrome P450 3A4 (503 aa, ~57 kDa) is encoded by the human CYP3A4 gene. This protein is involved in the oxidation of steroids, fatty acids and xenobiotics.NCI
DesignNote	Cytochrome P450 3A4 oxidizes etoposide and converts aflatoxin B1 to a genotoxic derivative.
code	C17573
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0159612
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