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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Azimexon
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Azimexon
UMLS_CUI
  • C0104835
CAS_Registry
  • 64118-86-1
FDA_UNII_Code
  • 4NJ842U6BZ
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39159
PDQ_Closed_Trial_Search_ID
  • 39159
Chemical_Formula
  • C9H14N4O
Legacy_Concept_Name
  • Azimexon
FULL_SYN
  • AZABNCI
  • AZIMEXONPTFDA4NJ842U6BZ
  • 2-Aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl]SNNCI
  • BM12531CNNCI
  • 2-Cyanaziridinyl-2-carbamoyl-aziridinyl-1-propaneSNNCI
  • AzimexonPTNCI
  • BM 12.531CNNCI
  • AzimexoneSYNCI
DEFINITION
  • Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma.NCI
code
  • C1347
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