About: Cytotoxic T-Lymphocyte

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Cytotoxic T-Lymphocyte
rdfs:subClassOf	Effector T-Lymphocyte CD8-Positive T-Lymphocyte
Semantic_Type	Cell
Display_Name	T-Lymphocyte, Cytotoxic
Preferred_Name	Cytotoxic T-Lymphocyte
UMLS_CUI	C0039195
ALT_DEFINITION	A type of immune cell that can kill certain cells, including foreign cells, cancer cells, and cells infected with a virus. Cytotoxic T lymphocytes can be separated from other blood cells, grown in the laboratory, and then given to a patient to kill cancer cells. A cytotoxic T lymphocyte is a type of white blood cell and a type of lymphocyte.NCI-GLOSS
Legacy_Concept_Name	Cytotoxic_T-Lymphocyte
FULL_SYN	Cytotoxic T-LymphocytePTNCI Cytotoxic T-LymphocytesSYNCI T-Lymphocyte, CytotoxicDNCTRM T-Lymphocytes, CytotoxicSYNCI Cytotoxic T-LymphocytesSYCTRM T-Lymphocytes, CytotoxicSYCTRM CTLSYNCI killer T cellPTNCI-GLOSSCDR0000634810 CTLSYCTRM Cytotoxic T CellSYNCI Cytolytic T-CellSYNCI Cytotoxic T CellsSYNCI cytotoxic T lymphocytePTNCI-GLOSSCDR0000634067 cytotoxic T cellPTNCI-GLOSSCDR0000045664 Cell-Mediated Lympholytic CellsSYCTRM
DEFINITION	Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. These cells are distinct from natural killer cells and from killer cells mediating antibody-dependent cell cytotoxicity.NCI
code	C12543
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0020989
is rdfs:subClassOf of	EBV-Specific Cytotoxic T-Lymphocyte Mature Cytotoxic T-Lymphocyte
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